651331-66-7

Usage

Molecular structure

1H-Indole-3-decanol, 5-methoxy-1-[(4-methoxyphenyl)sulfonyl]consists of an indole ring with a decanol side chain and a sulfonyl group attached to the 5-methoxy position of the indole ring.

Functional groups

The compound contains a decanol side chain, a sulfonyl group, and methoxy groups on both the sulfonyl and phenyl ring.

Complexity

The presence of multiple functional groups and the sulfonylated indole structure adds to the complexity of the compound.

Potential applications

This chemical compound may have applications in the fields of organic synthesis, pharmaceuticals, or agrochemicals due to its unique structure and potential reactivity as a sulfonylated indole derivative.

Need for further research

Additional studies are required to determine the specific uses and properties of 1H-Indole-3-decanol, 5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-.

Upstream product

• 67929-86-6 methyl 5-methoxyindole-2-carboxylate 
• 104876-11-1 (((9-bromononyl)oxy)methyl)benzene 
• 4382-54-1 5-methoxy-1H-indole-2-carboxylic acid 
• 651331-50-9 5-methoxy-1-(4-methoxybenzenesulfonyl)-1H-indole-3-carbaldehyde 
• 591-31-1 3-methoxy-benzaldehyde 
• 3937-56-2 1,9-Nonanediol 
• 55362-80-6 9-bromononan-1-ol 
• 10601-19-1 5-methoxyindole-3-carboxaldehyde 
• 1006-94-6 5-methoxylindole 

Relevant academic research and scientific papers

INDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME

An indole derivative represented by the following general formula (1) : wherein at least one of R1, R2, R3, and R4 represents an alkoxy group containing 1 to 20 carbon atoms, and other groups of the R1, R2, R3, and R4 represent hydrogen, an alkyl group containing 1 to 6 carbon atoms, acetyl group, or hydroxyl group; and either one of X and Y represents -(CH2)nOH wherein n is an integer of 0 to 30, and the other one of the X and Y represents hydrogen atom; or a salt thereof; and a drug and an agent for promoting differentiation of a stem cell containing such indole derivative or its salt as an effective component. The indole derivative (1) of the present invention has action of inducing differentiation of neural stem cell specifically into a neuron, and this indole derivative is useful as a prophylactic or therapeutic drug for brain dysfunction or neuropathy caused by loss or degeneration of the neuron.

Effects of indole fatty alcohols on the differentiation of neural stem cell derived neurospheres

In a search for inducers of neuronal differentiation to treat neurodegenerative diseases such as Alzheimer's disease, a series of indole fatty alcohols (IFAs) were prepared, 13c (n = 18) was able to promote the differentiation of neural stem cell derived neurospheres into neurons at a concentration of 10 nM. Analysis of the expression of the Notch pathway genes in neurospheres treated during the differentiation phase with 13c (n = 18) revealed a significant decrease in the transcription of the Notch 4 receptor.