651359-07-8

Upstream product

• 108-24-7 acetic anhydride 
• 651359-06-7 2-hydroxy-1-tert-butyldimethylsilyloxy-1-[3-methyl-2-oxo-5-phenyl-(4S,5R)-1,3-oxazolan-4-yl]-(1R)-dodecan-3-one 
• 651358-95-1 2-bromo-3-tert-butyldimethylsilyloxy-(4Ss)-(4-methylphenylsulfinyl)-1-phenyl-(1R,2R,3S)-butan-1-ol 
• 651359-04-5 2-tert-butyldimethylsilyloxy-2-[3-methyl-2-oxo-5-phenyl-(4S,5R)-1,4-oxazolan-4-yl]-acetaldehyde 
• 95482-80-7 1-(4-methylphenylsulfinyl)-4-phenyl-(2R,3E)-3-buten-2-ol 

Downstream Products

• 125356-66-3 (+)-preussin 

Relevant academic research and scientific papers

A novel and stereospecific synthesis of (+)-preussin

A novel and stereospecific approach to (+)-preussin that would permit the synthesis of analogs for structure activity relationship studies, is disclosed. The key step includes the regio- and stereoselective elaboration of a bromohydrin via intramolecular sulfinyl group participation.