65170-99-2

Upstream product

• 65171-10-0 (+/-)-4-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2(3H)-furanone 
• 119138-93-1 (+/-)-4-(3,4,5-trimethoxyphenyl)-3-methoxycarbonylbutanoic acid 
• 35274-53-4 2-bromo-3,4,5-tri-methoxybenzaldehyde 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 84736-30-1 (trimethoxy-3,4,5 benzylidene) α-hemisuccinate de methyle 

Downstream Products

• 84736-37-8 bis<(butanolidyl-4)-3 methyl>-6,6' hexamethoxy-2,3,4,2',3',4' biphenyle 
• 120-57-0 piperonal 
• 60229-65-4 4,5:4',5'-bis(methylenedioxy)-1,1'-biphenyl-2,2'-dicarboxaldehyde 
• 71209-04-6 <(butanolidyl-4)-3 methyl>-6 formyl-2' methylenedioxy-4',5' trimethoxy-2,3,4 biphenyle 

Relevant academic research and scientific papers

SYNTHESES TOTALES ET ETUDES DE LIGNANES BIOLOGIQUEMENT ACTIFS. APPLICATION DE L'α-HYDROXYALKYLATION DE β-BENZYL γ-BUTYROLACTONES A LA CREATION DES SQUELETTES PHENYL TETRALINE ET BISBENZOCYCLOOCTADIENE - 4. SYNTHESE TOTALE DE LA (+/-)-STEGANONE ET DE SES C

The biphenyl 16 (obtained from α-bromopiperonal and the aromatic iodide 14 by a modified Ullmann reaction) was cyclized by intramolecular hydroxyalkylation to the isomeric alcohols 17a and 17b.These were oxidized using Jones' reagent, to afford the enol 1

SYNTHESES TOTALES ET ETUDES DE LIGNANES BIOLOGIQUEMENT ACTIFS-I. APPLICATION DE LA REACTION D'ULLMANN A LA SYNTHESE DE BIARYLES PRECURSEURS DE LIGNANES BISBENZOCYCLOOCTADIENES

Several biaryls bearing various substituents on both rings were synthesized in a preparativ fashion, and in yields up to 88percent by a technical improvement on the classical Ullmann reaction.All these biaryls bear reactive functional groups (i.e. formyl, methoxycarbonyl, dimethoxycarbonylpropyl and butanolidylmethyl) in both the o and o' positions.The biaryls 9, 13, 21 and 26-33 are plausible synthons for bisbenzocyclooctadiene lignans such as schizandrin and steganacin.