651734-88-2Relevant articles and documents
USE OF KINASE INHIBITORS TO PROMOTE NEOCHONDROGENESIS
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Page/Page column 38; 39, (2010/10/20)
This invention provides methods for utilizing compounds that inhibit cyclin-dependent kinase and tyrosine kinase enzymes in the promotion of neochondrogenesis and the enhancement, protection and repair of cartilage. In certain embodiments the invention relates to methods of using compounds of formula (I): and pharmaceutically acceptable salts thereof, to promote neochondrogenesis, wherein, R1,R2, R3, R4, R5, R6, A, B, D, and E have any of the values defined therefor in the specification.