651749-33-6Relevant academic research and scientific papers
Inhibitors of HCV NS5B polymerase: Synthesis and structure-activity relationships of N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides
Chris Krueger,Madigan, Darold L.,Jiang, Wen W.,Kati, Warren M.,Liu, Dachun,Liu, Yaya,Maring, Clarence J.,Masse, Sherie,McDaniel, Keith F.,Middleton, Tim,Mo, Hongmei,Molla, Akhteruzzaman,Montgomery, Debra,Pratt, John K.,Rockway, Todd W.,Zhang, Rong,Kempf, Dale J.
, p. 3367 - 3370 (2006)
Substituted N-alkyl-4-hydroxyquinolon-3-yl-benzothiadiazine sulfamides were investigated as inhibitors of genotype 1 HCV polymerase. Structure-activity relationship patterns for this class of compounds are discussed.
UREIDO SUBSTITUTED BENZOIC ACID COMPOUNDS AND THEIR USE FOR NONSENSE SUPPRESSION AND THE TREATMENT OF DISEASE
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, (2010/02/06)
The invention encompasses ureido substituted benzoic acid compounds, compositions comprising the compounds and methods for treating or preventing diseases associated with nonsense mutations of mRNA by administering these compounds or compositions.
