651780-33-5

Usage

Uses

Used in Pharmaceutical Research:
Ethanone, 1-(6-bromo-1H-indazol-1-yl)is utilized as a chemical intermediate in the development of new pharmaceuticals, particularly for its potential pharmacological activities. Its unique structure may offer novel avenues for drug discovery, including the design of new therapeutic agents.
Used in Chemical Synthesis:
In the chemical industry, Ethanone, 1-(6-bromo-1H-indazol-1-yl)serves as a key building block for the synthesis of more complex organic compounds. Its reactivity and structural features make it a valuable component in the creation of advanced materials and specialty chemicals.
Used in Material Science:
Ethanone, 1-(6-bromo-1H-indazol-1-yl)may also find applications in material science, where its specific chemical and physical properties could contribute to the development of new materials with tailored properties for various uses, such as in electronics, coatings, or sensors.

Upstream product

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• 110-46-3 isopentyl nitrite 

Relevant academic research and scientific papers

Protected indazole boronic acid pinacolyl esters: Facile syntheses and studies of reactivities in Suzuki-Miyaura cross-coupling and hydroxydeboronation reactions

The paper describes a rapid and efficient synthesis for the isolation of protected indazolylboronic esters. These compounds were synthesized by reaction between prepared protected haloindazoles and bis(pinacolato)diboron. The effects of solvent, temperature, reaction time, and the nature of halogen atom as well as protecting group were investigated. Additionaly, these compounds reacted either with aryl halides in a Suzuki-Miyaura cross-coupling reaction or with hydrogen peroxide in a hydroxydeboronation reaction showing the potential access to new aryl and hydroxyindazole libraries. Georg Thieme Verlag Stuttgart.

6' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY

The present disclosure provides compounds having affinity for the 5-HT6 receptor which are of the formula (I): wherein R1—R4 A, B, D, E, and G are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.

FUSED HETEROARYL DERIVATIVES FOR USE AS P38 KINASE INHIBITORS IN THE TREATMENT OF I.A. RHEUMATOID ARTHRISTIS

Compounds of formula (I): wherein A is a 5-membered heteroaryl ring are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38, such as rheumatoid arthritis.