65180-43-0Relevant articles and documents
Synthetic method of aryl sulphobetaine in solvent-free system
-
Paragraph 0044; 0050, (2017/04/03)
The invention relates to a synthetic method of aryl sulphobetaine in a solvent-free system. The method comprises the steps that alkyl dimethyl tertiary amine and benzyl chloride which are close to the stoichiometric ratio react to synthetize alkyl dimethyl benzyl ammonium chloride at a low temperature, under high-speed stirring of a planetary stirrer and dilution of dry air in the solvent-free system, alkyl dimethyl benzyl ammonium chloride is added into chlorosulfonic acid close to the stoichiometric ratio step by step for a reaction, and alkyl dimethyl benzyl sulphobetaine is obtained. According to the method, no solvent is needed, the production cost is low, a small amount of residual chlorosulfonic acid obtained after a solvent-free reaction can be recycled through high-speed centrifugation, and the yield of alkyl dimethyl benzyl sulphobetaine can reach 98% or above.