65189-93-7

Usage

Physical state

Colorless liquid

Odor

Slight aromatic

Main use

Pharmaceutical industry (intermediate in the synthesis of medications and drugs)

Additional uses

Production of fragrances, flavors, and other fine chemicals

Potential applications

Organic synthesis (reagent in various chemical reactions)

Safety precautions

Harmful if swallowed, inhaled, or comes into contact with the skin

Upstream product

• 536-50-5 CH₃C₆H₄CH(CH₃)OH 
• 122-00-9 para-methylacetophenone 
• 40180-80-1 3-bromo-4-methylacetophenone 

Downstream Products

• 623943-05-5 3-(diphenylphosphino)-4-methylstyrene 
• 167960-11-4 3-bromo-4-methylstyrene 

Relevant academic research and scientific papers

Fast oxidation of secondary alcohols by the bromate-bromide system using cyclic microwave heating in acidic water

We report an improved, gentle, cyclic microwave activation technique for the oxidation of secondary alcohols using nonhazardous hypobromous acid (BrOH) as the reagent in acidic water. Several aliphatic and aromatic secondary alcohols were successfully oxidized to the corresponding ketones using this technique in high yields and with only minor amounts of side products.

Polystyrene-supported palladacycle catalysts

This invention relates to a recyclable palladacycle catalyst of formula in which each is a single bond or a double bond, provided that if one is a double bond, its neighboring is not a double bond; each of X and Z, independently, is —P(R′)—, —S—, —N(R′)—,

Preparation of polystyrene-supported soluble palladacycle catalyst for Heck and Suzuki reactions

A polystyrene-supported palladium complex soluble in tetrahydrofuran and N,N-dimethylacetamide and precipitated in diethyl ether or acetonitrile was prepared from two routes as an excellent and recyclable palladacycle catalyst for carbon-carbon bond formation in Heck and Suzuki reactions to give high yields of the desired products.

Polystyrene-supported recyclable palladacycle catalyst for Heck, Suzuki and Sonogashira reactions

A new type of soluble polystyrene-supported palladium complex as an excellent and recyclable palladacycle catalyst was discovered for carbon-carbon bond formation in Heck, Suzuki and Sonogashira reactions. Precipitation and filtration process for recycling the catalyst was also achieved.