6519-18-2

Basic information

• Product Name: 2-methylharmine
• Synonyms: N-METHYLHARMINE;N(2)-methylharmine
• CAS NO: 6519-18-2
• Molecular Formula: C₁₄H₁₄N₂O
• Molecular Weight: 226.27
• Mol File: 6519-18-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 446.2°C at 760 mmHg
• Flash Point: 223.6°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 3.73E-08mmHg at 25°C
• Refractive Index: 1.618
• CAS DataBase Reference: 2-methylharmine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methylharmine(6519-18-2)
• EPA Substance Registry System: 2-methylharmine(6519-18-2)

Safety Data

• Hazardous Substances Data: 6519-18-2(Hazardous Substances Data)

Usage

Definition

ChEBI: A member of the class of beta-carbolines that is 9H-beta-carboline substituted by a methoxy group at position 7 and methyl groups at positions 1 and 2. It is a semisynthetic derivative of harmine and has been shown to exhibit significant anti-HIV activity.

InChI:InChI=1/C14H14N2O/c1-9-14-12(6-7-16(9)2)11-5-4-10(17-3)8-13(11)15-14/h4-8H,1-3H3

Relevant articles and documents

Spectroscopic study of molecular associations between FMN and β-carbolines

The spectrophotometric and thermodynamic properties of molecular complexes of flavin mononucleotide (FMN) (riboflavin 5'-phosphate) with some β-carboline derivatives have been investigated in aqueous solution.The molecular associations have been examined by means of electronic absorption spectra, since in each a new charge-transfer band has been located, and also the variation of the fluorescenece emission of FMN on the solutions has been observed.The formation constants for the molecular complexes were determined from absorption data using the Foster-Hammick-Wardley method.The quenching phenomenon observed in FMN fluorescence is related to the concentration of the β-carboline derivatives, allowing the calculation of the quenching constants for FMN-β-carboline complexes.Thermodynamic parameters have been determined from the values of association constants for the molecular complexes at various temperatures.The influence of substituents in the β-carboline molecule on the stability of the complexes formed was also investigated.