65195-56-4 Usage
Uses
Used in Veterinary Medicine:
Avermectin B1b is used as an anthelmintic for the control of parasitic nematodes in livestock. It is a key component in various veterinary products, contributing to the effective treatment and prevention of parasitic infections in animals.
Brand names that contain Avermectin B1b include:
Avomec (Merck)
Bovitin (Merial)
Doratect (Merial)
Duomectin (Merial)
Duotin (Merial)
Endecto (Merck)
Enzec (Merck)
Enzek (Merck)
Parafoil (Merck)
Vertimil (Zectin, Merck)
Biological Activity
avermectin b1 is a mixture of avermectins containing >80% avermectin b1a and <20% avermectin b1b. b1a and b1b have very similar biological and toxicological properties.
in vitro
the avermectins are insecticidal and antihelmintic compounds derived from various laboratory broths fermented by the soil bacterium. avermectin b1 is a natural fermentation product of this bacterium.
in vivo
avermectin b1 therapy resulted in significant decreases in mean strongyle egg after treatment. all horses given ivermectin or avermectin b1 had zero strongyle egg counts 14 and 28 d after treatment. the oral administration of avermectin b1 appeared to be highly efficacious against intestinal strongyles and onchocera microfilaria [1].
references
[1] mogg td, pollitt cc, willmore jp, thompson h. efficacy of avermectin b1 given orally against equine intestinal strongyles and onchocera microfilaria. aust vet j. 1990;67(11):399-401.
Check Digit Verification of cas no
The CAS Registry Mumber 65195-56-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,1,9 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 65195-56:
(7*6)+(6*5)+(5*1)+(4*9)+(3*5)+(2*5)+(1*6)=144
144 % 10 = 4
So 65195-56-4 is a valid CAS Registry Number.
InChI:InChI=1/C47H70O14/c1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h11-14,16-18,24-25,27,29-30,32-44,48-49,51H,15,19-23H2,1-10H3/b12-11+,26-14+,31-13+/t25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42?,43-,44+,46?,47+/m0/s1
