Dihydrohordatin A is a chemical compound derived from the fungus Hordatin A, which is found in the barley pathogen Fusarium culmorum. It is a potent and selective inhibitor of the enzyme dihydroorotate dehydrogenase (DHODH), which plays a crucial role in the de novo pyrimidine synthesis pathway. This enzyme is essential for the proliferation of rapidly dividing cells, such as cancer cells and certain pathogens. Dihydrohordatin A has shown potential as an anticancer agent and an antimicrobial drug due to its ability to target DHODH, thereby inhibiting the growth of cancer cells and pathogens. Its unique mechanism of action and selectivity make it a promising candidate for further research and development in the fields of oncology and infectious diseases.
The CAS Registry Mumber 6520-17-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,5,2 and 0 respectively; the second part has 2 digits, 1 and 7 respectively. Calculate Digit Verification of CAS Registry Number 6520-17: (6*6)+(5*5)+(4*2)+(3*0)+(2*1)+(1*7)=78 78 % 10 = 8 So 6520-17-8 is a valid CAS Registry Number.
6520-17-8Upstream product
6520-17-8Downstream Products
6520-17-8Relevant academic research and scientific papers