65202-62-2

Usage

InChI:InChI=1/C8H10N2O4/c1-13-8(12)10-3-2-5-6(4-10)14-9-7(5)11/h2-4H2,1H3,(H,9,11)

Upstream product

• 65202-59-7 4-ethyl 1-methyl 3-oxopiperidine-1,4-dicarboxylate 

Downstream Products

• 64603-91-4 4,5,6,7-tetrahydroisoxazole<5,4-c>pyridin-3-ol 
• 91305-69-0 6-methoxycarbonyl-3-phenylsulfonyloxy-4,5,6,7-tetrahydroisoxazolo<5,4-c>pyridine 
• 91305-70-3 6-methoxycarbonyl-7-oxo-3-phenylsulfonyloxy-4,5,6,7-tetrahydroisoxazolo<5,4-c>pyridine 
• 91305-43-0 3-hydroxy-7-oxo-4,5,6,7-tetrahydroisoxazolo<5,4-c>pyridine 

Relevant academic research and scientific papers

Heterocyclic compounds

The compound Ia STR1 has been shown to possess GABA-related activity. The invention relates to Ia and derivatives thereof, covered by the formula STR2 in which R" is hydrogen, acetyl or a group of the general formula STR3 in which R5 is C1-8 alkyl; phenyl; phenyl substituted in the 4-position with halogen, lower alkoxy, or lower alkyl; or phenylalkyl in which the phenyl group may be substituted in the 4-position with halogen, lower alkoxy, or lower alkyl; and salts thereof. Novel intermediates for preparing I are STR4 in which Alk is a lower alkyl group and Z is hydrogen or an amino-protecting group; STR5 wherein Z is hydrogen or an amino-protecting group, T is a group convertible, by hydrolysis, into an oxy group, and Q is a leaving group which, on reaction with hydroxylamine, forms a hydroxamic acid group; STR6 wherein Z and T are as defined above; STR7 wherein Z is as defined above, and W is hydrogen or a group removable to yield the free hydroxy group, with the proviso that at least one of Z and W is different from hydrogen.