65206-60-2Relevant academic research and scientific papers
Air-induced double addition of P(O)-H bonds to alkynes: A clean and practical method for the preparation of 1,2-bisphosphorylethanes
Guo, Haiqing,Yoshimura, Aya,Chen, Tieqiao,Saga, Yuta,Han, Li-Biao
, p. 1502 - 1506 (2017)
An air-induced double addition of diphenyl phosphine oxide to various alkynes is reported. This reaction can proceed efficiently under metal- and solvent-free conditions, and is a clean and practically useful method for the preparation of the valuable 1,2
DOUBLE ADDITION OF PHOSPHINE OXIDE TO ALKYNE WITH BASE CATALYST
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Paragraph 0067; 0070, (2017/09/06)
PROBLEM TO BE SOLVED: To provide a method of synthesizing a phosphorus compound by double addition of phosphine oxide to alkyne with a base catalyst. SOLUTION: The present invention provides a method comprising the step of reacting alkyne and a phosphorus compound in an ether solvent in the presence of a catalytic amount of a base. The method of production according to the present invention (1) allows a reduction in remaining metal components in the product and (2) a reduction in production cost and (3) has an expanded scope of substrates in comparison with the conventional methods of production. Moreover, the obtained compounds may be used in flame retardants, lubricant additives, pharmaceutical intermediates, and catalyst raw materials. Furthermore, phosphine compounds that are obtained by reducing the compounds obtained by this reaction are compounds useful as ligands. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT
An efficient base-catalyzed double addition of H-phosphine oxides to alkynes
Yoshimura, Aya,Saga, Yuta,Sato, Yuki,Ogawa, Akiya,Chen, Tieqiao,Han, Li-Biao
supporting information, p. 3382 - 3384 (2016/07/11)
An efficient base-catalyzed double addition of H-phosphine oxides to alkynes is developed. In the presence of a catalytic amount of a base, the addition of various H-phosphine oxides to both aromatic and aliphatic alkynes took place efficiently to produce the corresponding bisphosphoryl compounds in excellent yields. This method provides an easy direct way to prepare bisphosphine oxides that are of high importance in organic synthesis.
