65219-93-4

Basic information

• Product Name: Benzoic acid, 2-(dimethylamino)-6-hydroxy-4-methyl-, ethyl ester
• CAS NO: 65219-93-4
• Molecular Formula: C12H17NO3
• Molecular Weight: 223.272
• Mol File: 65219-93-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(dimethylamino)-6-hydroxy-4-methyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(dimethylamino)-6-hydroxy-4-methyl-, ethyl ester(65219-93-4)
• EPA Substance Registry System: Benzoic acid, 2-(dimethylamino)-6-hydroxy-4-methyl-, ethyl ester(65219-93-4)

Safety Data

• Hazardous Substances Data: 65219-93-4(Hazardous Substances Data)

Upstream product

• 64274-36-8 (2-Ethoxycarbonyl-1-methyl-ethylidene)-dimethyl-ammonium; chloride 
• 14205-42-6 3-dimethylamino-crotonic acid ethyl ester 

Downstream Products

• 65220-02-2 2-Dimethylamino-6-hydroxy-4-methylbenzoesaeure 

Relevant articles and documents

Self-condensation of (β-Alkoxycarbonylalkylidene)ammonium Salts

Iminium chlorides or trifluoroacetates of type 2, formed by protonation of β-(alkoxycarbonyl)-enamines 1, have been proved to undergo condensation to give derivatives of 4-alkyl-2-amino-6-hydroxybenzoic acid 6 via elimination of ammonium salt and alcohol.The structures of 6 had been established by spectroscopic data as well as by further reactions.The range of application of this condensation reaction has been studied and the mechanism is discussed.In the primary step presumably a nucleophilic attack on the alkoxycarbonyl group of the iminium salt 2 takes place by the enamine 1 present in the equilibrium.Analogous reactions are also found for homologues of the enamine 1 (e.g. 11, 13 and 17) to give the condensation products 12, 14, 15, and 20.