65239-31-8 Usage
Uses
Used in Medicinal Chemistry:
(2-oxido-1,2,5-oxadiazole-3,4-diyl)bis[(4-fluorophenyl)methanone] is used as a building block for the development of new pharmaceutical agents due to its unique structural features and potential biological activity. The oxadiazole ring is known for its diverse pharmacological activities, which can be further enhanced by the presence of the fluorophenyl groups.
Used in Drug Development:
In the pharmaceutical industry, (2-oxido-1,2,5-oxadiazole-3,4-diyl)bis[(4-fluorophenyl)methanone] is utilized as a key intermediate in the synthesis of novel drug candidates. The incorporation of the fluorophenyl groups can impart specific chemical and biological properties to the compound, potentially leading to the discovery of new therapeutic agents with improved efficacy and selectivity.
Further research and studies are necessary to fully understand the behavior and potential uses of this chemical compound, as its unique structure and properties hold promise for various applications in the fields of medicinal chemistry and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 65239-31-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,2,3 and 9 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 65239-31:
(7*6)+(6*5)+(5*2)+(4*3)+(3*9)+(2*3)+(1*1)=128
128 % 10 = 8
So 65239-31-8 is a valid CAS Registry Number.
65239-31-8Relevant academic research and scientific papers
Does electrophilic activation of nitroalkanes in polyphosphoric acid involve formation of nitrile oxides?
Aksenov, Alexander V.,Aksenov, Dmitrii A.,Aksenov, Nicolai A.,Kirilov, Nikita K.,Kurenkov, Igor A.,Nobi, Mezvah A.,Rubin, Michael,Skomorokhov, Anton A.,Sorokina, Elena A.
, p. 35937 - 35945 (2021/12/02)
The mechanistic rationale involving activation of nitroalkanes towards interaction with nucleophilic reagents in the presence of polyphosphoric acid (PPA) was re-evaluated. Could nitrile oxide moieties be formed during this process? This experiment demonstrates that at least in some cases this could happen, as generated nitrile oxides were successfully intercepted as adducts of [3 + 2] cycloadditions. This journal is
Method for directly synthesizing furoxan from methyl ketone
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Paragraph 0055; 0056; 0057, (2020/01/08)
The invention discloses a method for directly synthesizing furoxan from methyl ketone, and belongs to the technical field of organic chemical synthesis. According to the method, methyl ketone is usedas a raw material, methyl ketone and a green nitration r
Solvent-free mechanochemical synthesis of diacylfuroxans
Gu, Zhen-Zhen,Guo, Feng-Chao,Zhang, Pu,Qin, Yu-Jun,Guo, Zhi-Xin
supporting information, p. 1687 - 1690 (2019/06/05)
Acetophenones with a variety of substituents could be converted to diacylfuroxans in a solvent-free reaction by combining the reagents Fe(NO3)3·9H2O and P2O5 under high-speed ball milling. This reacti