65276-59-7Relevant academic research and scientific papers
A green and efficient synthesis of furo[3,4-e]pyrazolo[3,4-b]-pyridine derivatives in water under microwave irradiation without catalyst
Shi, Feng,Wang, Qian,Tu, Shujiang,Zhou, Jianfeng,Jiang, Bo,Li, Chunmei,Zhou, Dianxiang,Shao, Qingqing,Cao, Longji
, p. 1103 - 1108 (2008/12/20)
(Chemical Equation Presented) A series of furo[3,4-e]pyrazolo[3,4-b] pyridine analogues of podophylloxin were synthesized via three-component reactions of aldehydes, 3-methyl-1-phenyl-1H-pyrazol-5-amine and tetronic acid in water under microwave irradiation without catalyst. This efficient synthesis not only offers an economical and green synthetic strategy to this class of significant compounds but also enriches the investigations on microwave-assisted synthesis in water.
