653-13-4 Usage
Uses
Used in Pharmaceutical Industry:
2,2-Difluoro-2-Chloroacetophenone is used as a key intermediate in the synthesis of various pharmaceutical compounds for its unique chemical properties, contributing to the development of new drugs with specific therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 2,2-Difluoro-2-Chloroacetophenone serves as a crucial component in the production of pesticides and other crop protection agents, leveraging its chemical reactivity to create effective solutions for agricultural applications.
Check Digit Verification of cas no
The CAS Registry Mumber 653-13-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 3 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 653-13:
(5*6)+(4*5)+(3*3)+(2*1)+(1*3)=64
64 % 10 = 4
So 653-13-4 is a valid CAS Registry Number.
653-13-4Relevant academic research and scientific papers
Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent
Miele, Margherita,Citarella, Andrea,Micale, Nicola,Holzer, Wolfgang,Pace, Vittorio
supporting information, p. 8261 - 8265 (2019/10/16)
The homologation of Weinreb amides into difluoromethylketones with a formal nucleophilic CHF2 transfer agent is reported. Activating TMSCHF2 with potassium tert-amylate enables a convenient access to the difluorinated homologation re