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2,2-Difluoro-2-Chloroacetophenone, also known as DFCP, is a chemical compound with the formula C8H6ClF2O. It is a white solid with a faint odor, known for its use in the synthesis of pharmaceuticals and agrochemicals. DFCP is recognized for its potent irritant properties, causing severe irritation and burns to the skin, eyes, and respiratory system upon exposure. As a potential environmental hazard, it is classified as a hazardous substance, necessitating careful handling, storage, and disposal in compliance with local regulations.

653-13-4

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653-13-4 Usage

Uses

Used in Pharmaceutical Industry:
2,2-Difluoro-2-Chloroacetophenone is used as a key intermediate in the synthesis of various pharmaceutical compounds for its unique chemical properties, contributing to the development of new drugs with specific therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 2,2-Difluoro-2-Chloroacetophenone serves as a crucial component in the production of pesticides and other crop protection agents, leveraging its chemical reactivity to create effective solutions for agricultural applications.

Check Digit Verification of cas no

The CAS Registry Mumber 653-13-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 3 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 653-13:
(5*6)+(4*5)+(3*3)+(2*1)+(1*3)=64
64 % 10 = 4
So 653-13-4 is a valid CAS Registry Number.

653-13-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-2,2-difluoroacetophenone

1.2 Other means of identification

Product number -
Other names o-Chlor-α,α-difluoracetophenon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:653-13-4 SDS

653-13-4Relevant academic research and scientific papers

Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent

Miele, Margherita,Citarella, Andrea,Micale, Nicola,Holzer, Wolfgang,Pace, Vittorio

supporting information, p. 8261 - 8265 (2019/10/16)

The homologation of Weinreb amides into difluoromethylketones with a formal nucleophilic CHF2 transfer agent is reported. Activating TMSCHF2 with potassium tert-amylate enables a convenient access to the difluorinated homologation re

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