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Ethyl 4-amino-2-(trifluoromethyl)pyrimidine-5-carboxylate is a chemical compound with the molecular formula C8H7F3N3O2. It is a white crystalline solid that is soluble in organic solvents. ETHYL 4-AMINO-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly those containing pyrimidine rings. Its structure features a pyrimidine core with a trifluoromethyl group at the 2-position, an amino group at the 4-position, and a carboxylate group at the 5-position, which is esterified with an ethyl group. The presence of the trifluoromethyl group can enhance the lipophilicity and metabolic stability of the final products, making it a valuable building block in the development of new drugs and pesticides.

653-95-2

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653-95-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 653-95-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,5 and 3 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 653-95:
(5*6)+(4*5)+(3*3)+(2*9)+(1*5)=82
82 % 10 = 2
So 653-95-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H8F3N3O2/c1-2-16-6(15)4-3-13-7(8(9,10)11)14-5(4)12/h3H,2H2,1H3,(H2,12,13,14)

653-95-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 4-amino-2-(trifluoromethyl)pyrimidine-5-carboxylate

1.2 Other means of identification

Product number -
Other names 4-amino-2-trifluoromethyl-pyrimidine-5-carboxylic acid ethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:653-95-2 SDS

653-95-2Relevant academic research and scientific papers

HETEROARYL COMPOUNDS FOR TREATMENT OF COMPLEMENT FACTOR D MEDIATED DISORDERS

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, (2021/08/27)

Compounds, methods of use, and processes for making inhibitors of complement factor D or a pharmaceutically acceptable salt or composition thereof are provided. The inhibitors described herein target factor D and inhibit or regulate the complement cascade. The inhibitors of factor D described herein reduce the excessive activation of complement.

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