65331-29-5

Basic information

• Product Name: 2(1H)-Quinazolinethione, 3,4,5,6,7,8-hexahydro-4-(4-methylphenyl)-8-[(4-methylphenyl)methylene] -
• CAS NO: 65331-29-5
• Molecular Formula: C23H24N2S
• Molecular Weight: 360.523
• Mol File: 65331-29-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2(1H)-Quinazolinethione, 3,4,5,6,7,8-hexahydro-4-(4-methylphenyl)-8-[(4-methylphenyl)methylene] -(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Quinazolinethione, 3,4,5,6,7,8-hexahydro-4-(4-methylphenyl)-8-[(4-methylphenyl)methylene] -(65331-29-5)
• EPA Substance Registry System: 2(1H)-Quinazolinethione, 3,4,5,6,7,8-hexahydro-4-(4-methylphenyl)-8-[(4-methylphenyl)methylene] -(65331-29-5)

Safety Data

• Hazardous Substances Data: 65331-29-5(Hazardous Substances Data)

Upstream product

• 42792-79-0 2,6-bis(4-methylbenzylidene)cyclohexanone 
• 17356-08-0 thiourea 
• 108-94-1 cyclohexanone 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 1191998-21-6 C₂₅H₂₆N₂OS 

Relevant articles and documents

An efficient and environmentally friendly procedure for the synthesis of some novel 8-Benzylidene-4-phenyl-3,4,5,6,7,8-hexahydro-1H-quinazolin-2-ones/ thiones using tetrabutylammonium hexatungstate as a reusable heterogeneous catalyst under solvent-free conditions

An efficient method for the preparation of 8-benzylidene-4-phenyl-3,4,5,6, 7,8-hexahydro-1H-quinazolin-2- ones/thiones from the reaction of aromatic aldehydes with cyclohexanone and urea or thiourea in the presence of Tetrabutylammonium hexatungstate, [TBA]2[W6O 19], as an efficient, inexpensive catalyst under thermal and solvent-free conditions has been developed. Good yields, short reaction times, straightforward workup, reusability of the catalyst, and green conditions are the most obvious advantages of this procedure.

Base-catalysed cyclocondensation of α,α′- bis(arylmethylene)cyclohexanones with thiourea: Formation of E-8-(arylmethylene)-4-aryl-1,2,3,4,5,6,7,8-octahydrobenzo[d]pyrimidine-2-thiones

Base-catalysed cyclocondensation of α,α′- bis(arylmethylene)cyclohexanones with thiourea has been found to generate E-8-(arylmethylene)-4-aryl-1,2,3,4,5,6,7,8-octahydrobenzo[d]pyrimidine-2- thiones in high yield, the structures of which have been established from their spectral data. However, corresponding cyclopentanones were found to be unreactive under similar reaction condition.