653564-10-4

Basic information

• Product Name: 2-METHYL-4-(TRIBUTYLSTANNYL)THIAZOLE
• Synonyms: 2-METHYL-4-(TRIBUTYLSTANNYL)THIAZOLE
• CAS NO: 653564-10-4
• Molecular Formula: C₁₆H₃₁NSSn
• Molecular Weight: 388.19904
• Product Categories: Stannanes
• Mol File: 653564-10-4.mol

Chemical Properties

• Boiling Point: 387.2°C at 760 mmHg
• Flash Point: 188°C
• Appearance: /
• Vapor Pressure: 7.45E-06mmHg at 25°C
• CAS DataBase Reference: 2-METHYL-4-(TRIBUTYLSTANNYL)THIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-4-(TRIBUTYLSTANNYL)THIAZOLE(653564-10-4)
• EPA Substance Registry System: 2-METHYL-4-(TRIBUTYLSTANNYL)THIAZOLE(653564-10-4)

Safety Data

• Hazardous Substances Data: 653564-10-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-METHYL-4-(TRIBUTYLSTANNYL)THIAZOLE is used as a building block in the synthesis of pharmaceuticals for its ability to facilitate various chemical transformations, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 2-METHYL-4-(TRIBUTYLSTANNYL)THIAZOLE is utilized as a reactive intermediate in the production of agrochemicals, aiding in the synthesis of compounds that can enhance crop protection and management.
Used in Fine Chemicals Industry:
2-METHYL-4-(TRIBUTYLSTANNYL)THIAZOLE is employed as a key component in the manufacture of fine chemicals, where its reactivity and structural features are leveraged to create specialty chemicals for various applications.

InChI:InChI=1/C4H4NS.3C4H9.Sn/c1-4-5-2-3-6-4;3*1-3-4-2;/h3H,1H3;3*1,3-4H2,2H3;/rC16H31NSSn/c1-5-8-11-19(12-9-6-2,13-10-7-3)16-14-18-15(4)17-16/h14H,5-13H2,1-4H3

Upstream product

• 1461-22-9 tributyltin chloride 
• 298694-30-1 4-bromo-2-methyl-1,3-thiazole 

Relevant articles and documents

NOVEL TETRAHYDROPYRIDOPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The present invention provides novel compounds having the general formula: wherein R1, R2 and R3 are as described herein, compositions including the compounds and methods of using the compounds.

MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS

Inhibitors of HCV replication of formula (I) and the N-oxides, salts, or stereoisomers thereof, wherein each dashed line (represented by ------) represents an optional double bond; X is N, CH and where X bears a double bond it is C; R1 is -OR6, -NH-SO2R7; R2 is hydrogen, and where X is C or CH, R2 may also be C1-6alkyl; R3 is hydrogen, C1-6alkyl, C1-6alkoxyC1-6alkyl, or C3-7cycloalkyl; n is 3, 4, 5, or 6; R4 and R5 independently from one another are hydrogen, halo, hydroxy, nitro, cyano, carboxyl, C1-6alkyl, C1-6alkoxy, C1-6alkoxyC1-6alkyl, C1-6alkylcarbonyl, C1-6alkoxy- carbonyl, amino, azido, mercapto, C1-6alkylthio, polyhaloC1-6alkyl, aryl or Het; W is aryl or Het; R6 is hydrogen; aryl; Het; C3-7cycloalkyl optionally substituted with C1-6alkyl; or C1-6alkyl optionally substituted with C3-7cycloalkyl, aryl or with Het; R7 is aryl; Het; C3-7cycloalkyl optionally substituted with C1-6alkyl; or C1-6alkyl optionally substituted with C3-7cycloalkyl, aryl or with Het; aryl is phenyl or naphthyl, each optionally substituted with 1-3 substituents; Het is a 5 or 6 membered saturated, partially unsaturated or completely unsaturated heterocyclic ring containing 1 - 4 heteroatoms each independently selected from N, O or S, and optionally substituted with 1 -3 substituents; pharmaceutical compositions containing compounds (I) and processes for preparing compounds (I). Bioavailable combinations of the inhibitors of HCV of formula (I) with ritonavir are also provided.