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2-Benzofurancarboxylic acid, 2-ethyl-2,3-dihydro-5-hydroxy, methyl ester, (2S)-(9CI) is a complex organic compound with the chemical formula C11H12O4. It is a chiral molecule, meaning it has a non-superimposable mirror image, and the (2S)-configuration indicates the presence of a specific stereochemistry at the chiral center. 2-Benzofurancarboxylicacid,2-ethyl-2,3-dihydro-5-hydroxy-,methylester,(2S)-(9CI) is characterized by a benzofuran ring, which is a fused structure of a benzene ring and a furan ring, and a carboxylic acid group. The 2-ethyl-2,3-dihydro part of the name suggests a saturated five-membered ring with an ethyl group attached to it. The 5-hydroxy group indicates the presence of a hydroxyl group at the 5th position of the benzofuran ring. The methyl ester part signifies that the carboxylic acid group is esterified with a methyl group. 2-Benzofurancarboxylicacid,2-ethyl-2,3-dihydro-5-hydroxy-,methylester,(2S)-(9CI) is likely to be used in the synthesis of various pharmaceuticals or other organic compounds due to its unique structure and functional groups.

653578-63-3

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653578-63-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 653578-63-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,3,5,7 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 653578-63:
(8*6)+(7*5)+(6*3)+(5*5)+(4*7)+(3*8)+(2*6)+(1*3)=193
193 % 10 = 3
So 653578-63-3 is a valid CAS Registry Number.

653578-63-3Downstream Products

653578-63-3Relevant academic research and scientific papers

COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS

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Page/Page column 35, (2008/06/13)

A class of compounds having Formula (I) and pharmaceutically acceptable salts thereof are useful as therapeutic compounds, particularly in the treatment of hyperlipidemia, hypercholesterolemia, dyslipidemia, and other lipid disorders, and in delaying the

Novel 2,3-dihydrobenzofuran-2-carboxylic acids: Highly potent and subtype-selective PPARα agonists with potent hypolipidemic activity

Shi, Guo Q.,Dropinski, James F.,Zhang, Yong,Santini, Conrad,Sahoo, Soumya P.,Berger, Joel P.,MacNaul, Karen L.,Zhou, Gaochao,Agrawal, Arun,Alvaro, Raul,Cai, Tian-Quan,Hernandez, Melba,Wright, Samuel D.,Moller, David E.,Heck, James V.,Meinke, Peter T.

, p. 5589 - 5599 (2007/10/03)

The design and synthesis of a novel class of 2,3-dihydrobenzofuran-2- carboxylic acids as highly potent and subtype-selective PPARα agonists are reported. Systematic study of structure-activity relationships has identified several key structural elements within this class for maintaining the potency and subtype selectivity. Select compounds were evaluated in animal models of dyslipidemia using Syrian hamsters and male Beagle dogs, and all these compounds displayed excellent cholesterol- and triglyceride-lowering activity at dose levels that were much lower than the marketed weak PPARα agonist fenofibrate.

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