65358-01-2

Upstream product

• 6632-68-4 6-amino-1,3-dimethyl-5-nitroso-1H-pyrimidine-2,4-dione 
• 104-87-0 4-methyl-benzaldehyde 
• 61541-41-1 6-azido-1,3-dimethylpyrimidine-2,4(1H,3H)-dione 
• 24994-04-5 5-(4-methylphenyl)-2H-tetrazole 
• 63875-13-8 1,3-Dimethyl-6-{N-methyl-N'-[1-p-tolyl-meth-(E)-ylidene]-hydrazino}-1H-pyrimidine-2,4-dione 
• 76952-22-2 5-Amino-1,3-dimethyl-6-(5-p-tolyl-tetrazol-2-yl)-1H-pyrimidine-2,4-dione 
• 96429-52-6 6,8-Dimethyl-4-oxy-3-p-tolyl-8H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione 
• 2216-94-6 phenylpropynoic acid ethyl ester 

Relevant academic research and scientific papers

Diels-Alder Reactions of 7-Azalumazines. Synthesis of Condensed Lumazines and 8-Deazalumazines

7-Azalumazines tethered at the C6 position with a series of dienophilic side chains undergo intramolecular Diels-Alder reactions to provide 6,7-annulated lumazines and 8-deazalumazines.The rates of these cycloaddition reactions are markedly faster than for previously reported cycloadditions of isomeric C7-tethered 6-azalumazines.On the other hand, 7-azalumazines do not undergo intermolecular Diels-Alder reactions with enamine dienophiles, whereas under identical conditions, 6-azalumazines react readily.Reasons for this striking reversal in reactivity observed for inter- and intramolecular Diels-Alder reactions of 6- vs 7-azalumazines are discussed.

Further Studies on the Ring Transformation of Pyrimido-as-triazine 4-Oxides to Pyrrolopyrimidines Involving 1,3-Dipolar Cycloaddition Reactions

The reaction of 3-alkyl(or aryl)-6,8-dimethylpyrimido-as-triazine-5,7(6H,8H)-dione 4-oxides (1a-f) with ethyl phenylpropiolate (EPP) in toluene afforded the unexpected 6-alkyl(or aryl)-5-benzoyl-7-(ethoxy-carbonyl)-1,3-dimethylpyrrolopyrimid

N-Bromosuccinimide in Heterocyclic Synthesis. Synthesis of Pyrazolopyrimidines, Pyrimido-as-triazines, and Pyrimidopyridazines from 6-Arylidenehydrazino-1,3-dimethyluracil Derivatives

Reactions of 6-arylidenehydrazino-1,3-dimethyluracil derivatives with N-bromosuccinimide leading to pyrazolopyrimidines, pyrimido-as-triazines, and pyrimidopyridazines are described.

A NEW SYNTHESIS OF FERVENULINS AND ALLOXAZINES. THERMOLYSIS AND PHOTOLYSIS OF 6-AZIDO-1,3-DIMETHYLURACIL WITH TETRAZOLES AND BENZOTRIAZOLES

Thermolysis of 6-azido-1,3-dimethyluracil(1) in the presence of 5-substituted tetrazoles(2) gave 3-substituted fervenulins(4), which were also synthesized from the intermediates(3) prepared by photolysis of (1) with (2).Irradiation of (1) with benzotriazoles(6) in tetrahydrofuran gave 6-(benzotriazol-1-yl)uracils(7), which were irradiated in methanol to afford alloxazines (8).