653597-74-1Relevant academic research and scientific papers
Synthesis of Side Chain Substituted 3-Butylisocoumarins and Absolute Configurations of Natural Isocoumarins from Artemisia dracunculus
Lutz-Kutschera, Gerda,Engelmeier, Doris,Hadacek, Franz,Werner, Andreas,Greger, Harald,Hofer, Otmar
, p. 1195 - 1206 (2007/10/03)
A series of 3-hydroxy- and 3-bromobutyl-substituted isocoumarins was synthesized. The absolute configurations of three isocoumarin derivatives from Artemisia dracunculus, namely (-)-epoxyartemidin, (-)-2′- methoxydihydroartemidin, and (+)-3′-hydroxyartemidin were determined by chemical means via derivatization, kinetic racemate resolution (Horeau method), and comparison of the circular dichroism (CD) spectra.
