65360-31-8 Usage
Uses
Used in Oncology:
Daunorubicin is used as an anticancer agent, particularly effective against leukemia and other forms of cancer such as breast and lung cancer. It functions by disrupting the synthesis of DNA and RNA in cancer cells, leading to cell death and thus helping to combat the progression of the disease.
Used in Chemotherapy Regimens:
Daunorubicin is an important component of many chemotherapy regimens due to its significant anticancer effects. It is administered through intravenous injection and has been instrumental in improving the outcomes for patients with certain types of cancer.
Used in Pharmaceutical Research and Development:
The potent anticancer properties of daunorubicin make it a valuable compound for further research and development in the pharmaceutical industry. Scientists and researchers continue to explore its potential applications and mechanisms of action to enhance its efficacy and reduce side effects in cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 65360-31-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,3,6 and 0 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 65360-31:
(7*6)+(6*5)+(5*3)+(4*6)+(3*0)+(2*3)+(1*1)=118
118 % 10 = 8
So 65360-31-8 is a valid CAS Registry Number.
InChI:InChI=1/C21H20O7/c1-3-21(27)7-10-13(11(22)8-21)19(25)16-15(18(10)24)17(23)9-5-4-6-12(28-2)14(9)20(16)26/h4-6,11,22,24-25,27H,3,7-8H2,1-2H3
65360-31-8Relevant academic research and scientific papers
SYNTHETIC ANTHRACYCLINONES-XXVII. ANTHRACYCLINONES BY INTRAMOLECULAR MARSCHALK REACTION. SYNTHESIS OF THE FEUDOMYCINONES AND RHODOMYCINONES.
Krohn, Karsten,Priyono, Wahyudi
, p. 4609 - 4616 (2007/10/02)
1,4,5-Trihydroxy-9,10-anthraquinone is transformed regioselectively to the α-hydroxy dichlorides 18-21, which are cyclized to yield predominantely the naturally configurated 9,10-trans-diols 1,3,26, and 27 (80 to 96percent d.e.).The monotrifluoroacetates 38-40 derived from the trans-diols are hydroxylated via bromination at C-7 to yield almost exclusively the 7,9-cis-9,10-trans-triols α1-rhodomycinone (4), feudomycinone D (7), and 4-O-methyl-β-rhodomycinone (42).The feudomycinones A (5) and C (6) are obtained with less chemo- and stereoselectivity by hydroxylation of the 10-deoxycompounds 33 and 34.
