65364-66-1

Basic information

• Product Name: ETHYL 2-(5-BROMOPYRIMIDIN-2-YL)-2-CYANOACETATE
• Synonyms: ETHYL 2-(5-BROMOPYRIMIDIN-2-YL)-2-CYANOACETATE
• CAS NO: 65364-66-1
• Molecular Formula: C9H8BrN3O2
• Molecular Weight: 270.08272
• Mol File: 65364-66-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 362.931 °C at 760 mmHg
• Flash Point: 173.295 °C
• Appearance: /
• Density: 1.57 g/cm³
• CAS DataBase Reference: ETHYL 2-(5-BROMOPYRIMIDIN-2-YL)-2-CYANOACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-(5-BROMOPYRIMIDIN-2-YL)-2-CYANOACETATE(65364-66-1)
• EPA Substance Registry System: ETHYL 2-(5-BROMOPYRIMIDIN-2-YL)-2-CYANOACETATE(65364-66-1)

Safety Data

• Hazardous Substances Data: 65364-66-1(Hazardous Substances Data)

Usage

General Description

ETHYL 2-(5-BROMOPYRIMIDIN-2-YL)-2-CYANOACETATE is a chemical compound with the molecular formula C9H8BrN3O2. It is a cyanoacrylate compound with a bromopyrimidine moiety attached to an ethyl cyanoacetate group. ETHYL 2-(5-BROMOPYRIMIDIN-2-YL)-2-CYANOACETATE is commonly used in organic synthesis as a building block for the construction of various heterocyclic compounds. It is also a precursor for the synthesis of pharmaceuticals and agrochemicals. Additionally, it has potential applications in the field of medicinal chemistry and drug discovery due to its structural properties and functional groups. ETHYL 2-(5-BROMOPYRIMIDIN-2-YL)-2-CYANOACETATE is considered to be a valuable chemical intermediate for the preparation of diverse bioactive molecules.

Upstream product

• 105-56-6 ethyl 2-cyanoacetate 
• 32779-37-6 2,5-dibromopyrimidine 
• 32779-36-5 5-Bromo-2-chloropyrimidine 

Downstream Products

• 831203-15-7 2-(5-bromopyrimidin-2-yl)acetonitrile 

Relevant articles and documents

NEW HETEROCYCLYLETHYLBENZAMIDE DERIVATIVES

A compound of general formula (I) : Rl R4 O N- (D A process for preparing this compound. A fungicide composition comprising a compound of general formula (I). A method for treating plants by applying a compound of general formula (I) or a composition comp

TAUTOMERISM OF AZINE DERIVATIVES. 6.* TAUTOMERISM OF 2-PYRIMIDINYLMETHANE DERIVATIVES

The existence of a pyrimidinyl-pyrimidinylidene tautomeric equilibrium in solutions of 2-pyrimidinylcyanoacetic acid esters in CDCl3 was observed.Unsymmetrically substituted compounds form two types of ylidene tautomers that differ with respect to the position of the NH proton, the ratio between which is controlled by the substituents in the 4(6) position.The introduction of both donor and acceptor substituents into the 5 position of the pyrimidine ring increase the amount of the pyrimidine form.The same thing occurs when the polarity of the solvent is decreased.The addition of DMSO or DMF to CDCl3 leads to conversion of the intrachelate ylidene tautomers to unchelated tautomers.Protonation (CF3COOH) shifts the equilibrium to favor the ylidene tautomers has higher basicity.