65383-73-5

Basic information

• Product Name: 7-ETHOXY-6-METHOXY-2,2-DIMETHYLCHROMENE
• Synonyms: Precocene III;7-Ethoxy-6-methoxy-2,2-dimethylchromene,99%;7-Ethoxy-6-Methoxy-2,2-diMethylchroMene, 99% 250MG;7-ETHOXY-6-METHOXY-2,2-DIMETHYLCHROMENE;7-ethoxyprecocene;7-ETHOXY-6-METHOXY-2,2-DIMETHYLCHROMENE 99%;ethoxyprecocene;7-Ethoxy-6-methoxy-2,2-dimethyl-2H-1-benzopyran
• CAS NO: 65383-73-5
• Molecular Formula: C₁₄H₁₈O₃
• Molecular Weight: 234.29
• EINECS: 265-728-5
• Mol File: 65383-73-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 316.61°C (rough estimate)
• Flash Point: >113 °C
• Appearance: /
• Density: 0.92
• Vapor Pressure: 0.000752mmHg at 25°C
• Refractive Index: 1.5547-1.5567
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 7-ETHOXY-6-METHOXY-2,2-DIMETHYLCHROMENE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-ETHOXY-6-METHOXY-2,2-DIMETHYLCHROMENE(65383-73-5)
• EPA Substance Registry System: 7-ETHOXY-6-METHOXY-2,2-DIMETHYLCHROMENE(65383-73-5)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 65383-73-5(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR BROWN LIQUID

InChI:InChI=1/C14H18O3/c1-5-16-13-9-11-10(8-12(13)15-4)6-7-14(2,3)17-11/h6-9H,5H2,1-4H3

Upstream product

• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 533-31-3 Sesamol 
• 65383-61-1 6,7-dimethoxy-2,2-dimethyl-4-chromanone 
• 112979-30-3 3,4-dioxymethylene phenyl 3-methyl-2-butenoate 
• 112979-31-4 1-(2-hydroxy-4,5-methylenedioxyphenyl)-3-methyl-2-buten-1-one 
• 73673-87-7 2,2-dimethyl-6,7-methylenedioxy-4-chromanone 
• 118948-72-4 1-(2',4',5'-trihydroxyphenyl)-3-methyl-1-oxo-2-butene 
• 118948-74-6 7-ethoxy-6-hydroxy-2,2-dimethyl-4-chromanone 
• 533-73-3 1,2,4-Trihydroxybenzene 
• 541-47-9 3-Methylbutenoic acid 
• 76348-95-3 2,2-Dimethyl-6,7-dihydroxy-4-chromanone 
• 142273-02-7 Formic acid 7-ethoxy-2,2-dimethyl-2H-chromen-6-yl ester 
• 142273-04-9 7-Ethoxy-2,2-dimethyl-2H-chromene-6-carbaldehyde 
• 142273-03-8 7-Ethoxy-2,2-dimethyl-2H-chromen-6-ol 

Relevant articles and documents

Efficient synthesis of precocenes

Precocenes and related intermediates were synthesised in good yields using hydrogen peroxide, selenium dioxide and methylene chloride combination in the key step.

Chromene derivatives and pesticidal composition comprising the same

The invention relates to a process for the preparation of chromenes of the general Formula V STR1 (wherein R1 and R2 are hydrogen, optionally halogeno substituted C1-6 alkyl or aryl; R3 and R7 stand for hydrogen, halogen or C1-6 alkyl; R4 represents C1-8 alkyl, aryl, aralkyl or a group containing a carbonyl group; R5 and R6 stand for C1-10 alkyl, aryl, amino, hydroxyalkyl, alkoxyalkenyl, alkylmercaptoalkyl, acyl, carboxy or an ester group or a halogen atom; n is 0 or 1) which comprises (a) for the preparation of compounds, in which R5 and R6 stand for different groups, reacting a compound of the general Formula I STR2 with an approximately equimolar, preferably 0.8-1.5 molar amount of a reactant of the general Formula R5 --X-related to the amount of the compound of the general Formula I (wherein R5 has the same meaning as stated above X is halogen) and reacting the O-monosubstituted compound of the general Formula III STR3 (wherein R1 -R6 and n are as stated above) obtained with a 1.1-1.5 molar amount of a compound of the general Formula III (wherein R6 and X are as stated above); or (b) for the preparation of compounds, in which R5 and R6 stand for the same group, reacting a chromanone of the general Formula I (wherein R1 -R4 and m have the meaning as stated above) with a 2-3 molar amount of a compound of the general Formula R5 --X-related to the amount of the compound of the general Formula I (wherein R5 and X are as stated above), preferably in the presence of a base, a catalyst and a solvent, and thereafter reducing the O-substituted chromanone derivative of the general Formula III thus obtained (wherein R1 -R6 and n are as stated above) and dehydrating the chromanol derivative of the general Formula IV STR4 thus obtained (wherein R1 -R6 and n are as stated above) in acidic-aqueous medium. The compounds of the general Formula V are partly new and useful for the preparation of pesticides.