654055-01-3

Basic information

• Product Name: MORIN R. G.
• Synonyms: MORIN R. G.;MORIN FLUKA, FOR MICROSCOPY;2μ,3,4μ,5,7-Pentahydroxyflavone dihydrate, 2μ,3,4μ,5,7-Pentahydroxyflavone;Morin hydrate,95%;Morin;Motin;Morin hydrate,2′,3,4′,5,7-Pentahydroxyflavone;2′-Hydroxypelargidenolon
• CAS NO: 654055-01-3
• Molecular Formula: C15H12O8
• Molecular Weight: 320.25098
• EINECS: 207-542-9
• Mol File: 654055-01-3.mol

Chemical Properties

• Melting Point: 299-300 °C (dec.)(lit.)
• Boiling Point: 645.5 °C at 760 mmHg
• Flash Point: 249.3 °C
• Appearance: yellow/
• Density: 1.799 g/cm³
• Storage Temp.: room temp
• Solubility: methanol: soluble50mg/mL
• Merck: 14,6269
• BRN: 327474
• CAS DataBase Reference: MORIN R. G.(CAS DataBase Reference)
• NIST Chemistry Reference: MORIN R. G.(654055-01-3)
• EPA Substance Registry System: MORIN R. G.(654055-01-3)

Safety Data

• Hazard Codes: Xi,T
• Statements: 36/37/38-25
• Safety Statements: 26-36-45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• RTECS: LK8749000
• HazardClass: 9
• PackingGroup: III
• Hazardous Substances Data: 654055-01-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
MORIN R. G. is used as an antitumor agent for investigating its functionality in human cancer cell lines. It is employed in cell viability and apoptosis assays to study its potential to inhibit tumor growth and induce cell death in cancer cells.
Used in Neurological Research:
MORIN R. G. is used as a fluorescence stain to detect aluminum in motor neurons and lumbar cord, which can help in understanding the role of aluminum in neurodegenerative diseases.
Used in Auditory Research:
MORIN R. G. is used to study its protective effect on neuronal hearing loss, suggesting its potential in preventing or treating hearing impairments related to oxidative stress or other factors.
Used in Stem Cell Research:
MORIN R. G. is used to study its impact on neural stem cells (NSCs) proliferation and differentiation, indicating its potential role in promoting neural regeneration and repair in the central nervous system.

Biochem/physiol Actions

Morin hydrate is a flavonoid with antioxidant properties. It has been shown to protect cells against oxygen radical damage. Morin not only scavenges oxyradicals, but also moderately inhibits xanthine oxidase, a free-radical generating enzyme. At concentrations of 75-100 micromolar, morin inhibits oxidation of low density lipoprotein (LDL) by free radicals or Cu2+. Morin has been reported to inhibit rat brain phospha-tidyl-inositol-phos-phate kinase activity in vitro and in vivo.