654065-37-9Relevant academic research and scientific papers
Palladium-Catalyzed Atom-Transfer Radical Cyclization at Remote Unactivated C(sp3)?H Sites: Hydrogen-Atom Transfer of Hybrid Vinyl Palladium Radical Intermediates
Ratushnyy, Maxim,Parasram, Marvin,Wang, Yang,Gevorgyan, Vladimir
supporting information, p. 2712 - 2715 (2018/03/02)
A novel mild, visible-light-induced palladium-catalyzed hydrogen atom translocation/atom-transfer radical cyclization (HAT/ATRC) cascade has been developed. This protocol involves a 1,5-HAT process of previously unknown hybrid vinyl palladium radical intermediates, thus leading to iodomethyl carbo- and heterocyclic structures.
Stereoselective preparation of functionalized acyclic alkenylmagnesium reagents using i-PrMgCl-LiCl
Ren, Hongjun,Krasovskiy, Arkady,Knochel, Paul
, p. 4215 - 4217 (2007/10/03)
(Chemical Equation Presented) Acyclic functionalized alkenyl iodides are converted with high stereoselectivity to the corresponding functionalized alkenylmagnesium derivatives by the reaction with i-PrMgCl-LiCl between -40 and -20°C. Functional groups such as a nitrile, chloride, iodide, and ester are readily tolerated. The conversion of an alkenyl iodide bearing a keto group to the corresponding silylated cyanohydrin allows preparation of the corresponding Grignard reagent affording, after acylation and deprotection, unsaturated 1,4-diketones.
Total synthesis of (-)-incarvilline, (+)-incarvine C, and (-)-incarvillateine
Ichikawa, Masaya,Takahashi, Masaki,Aoyagi, Sakae,Kibayashi, Chihiro
, p. 16553 - 16558 (2007/10/03)
The first total syntheses of new monoterpene alkaloids (-)-incarvilline, (+)-incarvine C, and (-)-incarvillateine, corresponding to the natural enantiomers, have been accomplished. The strategy for the synthesis of these natural products utilized 6-epi-in
