654069-16-6

Basic information

• Product Name: Benzoic acid, 3-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-
• CAS NO: 654069-16-6
• Molecular Formula: C14H22O3Si
• Molecular Weight: 266.412
• Mol File: 654069-16-6.mol

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-(654069-16-6)
• EPA Substance Registry System: Benzoic acid, 3-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-(654069-16-6)

Safety Data

• Hazardous Substances Data: 654069-16-6(Hazardous Substances Data)

Upstream product

• 619-21-6 m-formylphenyl benzoic acid 
• 28286-79-5 3-(Hydroxymethyl)benzoic acid 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 654069-14-4 (2E)-4-methoxy-2-[4-(methylsulfonyl)phenyl]-4-oxo-3-phenylbut-2-enyl-3-({[tert-butyl(dimethyl)silyl]oxy}methyl)benzoate 
• 654068-91-4 (2Z)-4-methoxy-2-[4-(methylsulfonyl)phenyl]-4-oxo-3-phenylbut-2-enyl 3-({[tert-butyl(dimethyl)silyl]oxy}methyl)benzoate 

Relevant articles and documents

Diphenyl urea anti-tumor micromolecule inhibitor and preparation method thereof (by machine translation)

The invention discloses a diphenyl urea anti-tumor small molecule inhibitor. The small molecule inhibitor may be represented formula I, Formula II, or Formula III. The small-molecule inhibitor specifically targets UBABA3, has good anti-tumor activity, and can be used as a good anti-tumor treatment small molecule inhibitor in the half inhibition concentration (IC50 5 μm) of various human non-small cell lung cancer cells. The small molecule inhibitor effect target is clear, and is different from MLNNNNN4924, and NAE enzyme activity inhibition mechanisms, respectively, are inhibited. Neddddylation modification cullin in the framework structure of the ubiquitin-modified key enzyme CRL ligase can be effectively inhibited, so that activation, CRL ligase activation is inhibited, and tumor growth inhibition effect is achieved. (by machine translation)