654073-29-7

Upstream product

• 654073-28-6 2-(2,3-difluoro-benzylsulfanyl)-pyrimidine-4,6-diol 

Downstream Products

• 878386-11-9 4-chloro-2-[(2,3-difluorobenzyl)thio]-6-(methylthio)pyrimidine 
• 878387-44-1 2-({6-chloro-2-[(2,3-difluorobenzyl)thio]pyrimidin-4-yl}oxy)ethanol 
• 1204707-78-7 (2R,3R)-3-({6-chloro-2-[(2,3-difluorobenzyl)thio]pyrimidin-4-yl}amino)butane-1,2-diol 
• 1204707-80-1 6-chloro-2-[(2,3-difluorobenzyl)thio]-N-{(1R)-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethyl}pyrimidin-4-amine 
• 1204707-82-3 6-chloro-2-[(2,3-difluorobenzyl)thio]-N-{(1R)-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]ethyl}pyrimidin-4-amine 
• 1204707-86-7 6-chloro-2-[(2,3-difluorobenzyl)thio]-N-{(1S)-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethyl}pyrimidin-4-amine 
• 1204707-88-9 6-chloro-2-[(2,3-difluorobenzyl)thio]-N-{(1S)-1-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]ethyl}pyrimidin-4-amine 
• 878385-81-0 4-chloro-2-[(2,3-difluorobenzyl)thio]-6-{(1R)-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethoxy}pyrimidine 

Relevant academic research and scientific papers

PYRIMIDINE SULPHONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS

A compound of formula (1), or a pharmaceutically acceptable salt, solvate or in vivo hydrolysable ester thereof and pharmaceutical compositions comprising these, all for use in the treatment of chemokine mediated diseases and disorders.

PYRIMIDYL SULPHONE AMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS

A compound of formula (I), pharmaceutically acceptable salt, solvate or in vivo hydrolysable ester thereof for the treatment of asthma, allergic rhinitis, COPD, inflammatory bowel disease, irritable bowel syndrome, osteoarthritis, osteoporosis, rheumatoid