Basic information

Product Name: (7-methyl-5-methylidene-2,3-dihydro-1H-1,4-diazepine-1,4(5H)-diyl)bis[(4-chlorophenyl)methanone]
Synonyms:
CAS NO:65426-77-9
Molecular Formula: C₂₁H₁₈Cl₂N₂O₂
Molecular Weight: 401.2858
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: 574.7°C at 760 mmHg
Flash Point: 301.4°C
Appearance: N/A
Density: 1.35g/cm³
Vapor Pressure: 3.26E-13mmHg at 25°C
Refractive Index: 1.652
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (7-methyl-5-methylidene-2,3-dihydro-1H-1,4-diazepine-1,4(5H)-diyl)bis[(4-chlorophenyl)methanone](CAS DataBase Reference)
NIST Chemistry Reference: (7-methyl-5-methylidene-2,3-dihydro-1H-1,4-diazepine-1,4(5H)-diyl)bis[(4-chlorophenyl)methanone](65426-77-9)
EPA Substance Registry System: (7-methyl-5-methylidene-2,3-dihydro-1H-1,4-diazepine-1,4(5H)-diyl)bis[(4-chlorophenyl)methanone](65426-77-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 65426-77-9(Hazardous Substances Data)

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65426-77-9 Usage

Uses

Used in Research Applications:
Ro 5-4864 is used as a research tool for studying the function of the peripheral benzodiazepine receptor (PBR) and its potential role in different physiological and pathological processes. Its high affinity for PBR allows researchers to investigate the receptor's involvement in various conditions.
Used in Pharmaceutical Applications:
Ro 5-4864 is being investigated as a potential therapeutic agent for conditions such as neurodegenerative diseases, anxiety disorders, and inflammation-related conditions. Its demonstrated anti-inflammatory, neuroprotective, and anxiolytic effects in animal models make it a promising candidate for further research and development in these areas.
Used in Drug Delivery Systems:
In order to enhance the applications and efficacy of Ro 5-4864, novel drug delivery systems are being developed. These systems aim to improve the compound's delivery, bioavailability, and therapeutic outcomes by employing various organic and metallic nanoparticles as carriers for Ro 5-4864 delivery.
Used in Neuroprotection:
Ro 5-4864 is used in the field of neuroprotection to study its potential benefits in protecting neurons from damage and degeneration. Its neuroprotective effects in animal models have shown promise for its use in treating neurodegenerative diseases.
Used in Anxiety Treatment:
The anxiolytic effects of Ro 5-4864 make it a candidate for use in the treatment of anxiety disorders. Its potential role in modulating the peripheral benzodiazepine receptor (PBR) could provide new insights into the development of anxiolytic medications.
Used in Inflammation Management:
Due to its anti-inflammatory properties, Ro 5-4864 is being explored for its potential use in managing inflammation-related conditions. Its ability to modulate the PBR may offer new therapeutic approaches for treating inflammatory diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 65426-77-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,4,2 and 6 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 65426-77:
(7*6)+(6*5)+(5*4)+(4*2)+(3*6)+(2*7)+(1*7)=139
139 % 10 = 9
So 65426-77-9 is a valid CAS Registry Number.

65426-77-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name	[4-(4-chlorobenzoyl)-7-methyl-5-methylidene-2,3-dihydro-1,4-diazepin-1-yl]-(4-chlorophenyl)methanone

1.2 Other means of identification

Product number	-
Other names	1,3,4,5-tetrahydro-1H-1,4-diazepine

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:65426-77-9 SDS

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