654651-45-3

Basic information

• Product Name: 2-benzyloxycarbonylamino-2-methyl-propionic acid 4-oxo-4H-pyrido[3,2-d][1,2,3]triazin-3-yl ester
• Synonyms: 2-benzyloxycarbonylamino-2-methyl-propionic acid 4-oxo-4H-pyrido[3,2-d][1,2,3]triazin-3-yl ester
• CAS NO: 654651-45-3
• Molecular Weight: 383.363
• Mol File: 654651-45-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-benzyloxycarbonylamino-2-methyl-propionic acid 4-oxo-4H-pyrido[3,2-d][1,2,3]triazin-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyloxycarbonylamino-2-methyl-propionic acid 4-oxo-4H-pyrido[3,2-d][1,2,3]triazin-3-yl ester(654651-45-3)
• EPA Substance Registry System: 2-benzyloxycarbonylamino-2-methyl-propionic acid 4-oxo-4H-pyrido[3,2-d][1,2,3]triazin-3-yl ester(654651-45-3)

Safety Data

• Hazardous Substances Data: 654651-45-3(Hazardous Substances Data)

Upstream product

• 15030-72-5 Z-Aib-OH 
• 655244-89-6 3-hydroxy-4-oxo-3,4-dihydro-5-azabenzo-1,2,3-triazine 
• 1462-86-8 3-amino-pyridine-2-carboxylic acid 
• 98140-94-4 3-amino-2-picolinehydroxamic acid 
• 27507-15-9 ethyl 3-aminopyridine-2-carboxylate 

Relevant articles and documents

3-Hydroxy-4-oxo-3,4-dihydro-5-azabenzo-1,2,3-triazene

The known but long-neglected compound HODhat was shown to be in certain situations a useful peptide coupling additive. Uronium and phosphonium salts with HODhat built into the system were also useful stand-alone coupling reagents. Comparisons with related additives and coupling reagents showed that the new systems were sometimes more and sometimes less effective than previously described systems in the case of stepwise and segment couplings. Applications to assembly of the model decapeptide ACP showed that HDATU was far more effective than HDTU and more effective than HATU under some conditions.