654669-12-2Relevant academic research and scientific papers
Furo[2,3-b]pyridine-based cannabinoid-1 receptor inverse agonists: Synthesis and biological evaluation. Part 1
Debenham, John S.,Madsen-Duggan, Christina B.,Toupence, Richard B.,Walsh, Thomas F.,Wang, Junying,Tong, Xinchun,Kumar, Sanjeev,Lao, Julie,Fong, Tung M.,Xiao, Jing Chen,Huang, Cathy R.-R.C.,Shen, Chun-Pyn,Feng, Yue,Marsh, Donald J.,Stribling, D. Sloan,Shearman, Lauren P.,Strack, Alison M.,Goulet, Mark T.
scheme or table, p. 1448 - 1452 (2010/07/06)
The synthesis, SAR and binding affinities of cannabinoid-1 receptor (CB1R) inverse agonists based on furo[2,3-b]pyridine scaffolds are described. Food intake, mechanism specific efficacy, pharmacokinetic, and metabolic evaluation of several of these compo
