Basic information

Product Name: FMOC-DAP(MTT)-OH
Synonyms: N-ALPHA-FMOC-N-BETA-4-METHYLTRITYL-L-ALPHA,BETA-DIAMINOPROPIONIC ACID;N-ALPHA-FMOC-N-BETA-4-METHYLTRITYL-L-DIAMINOPROPIONIC ACID;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-BETA(4-METHYL-TRITYL)-L-2,3-DIAMINOPROPIONIC ACID;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-BETA-(P-METHYLTRITYL)-L-2,3-DIAMINOPROPIONIC ACID;FMOC-DPR(MTT)-OH;FMOC-DAP(MTT)-OH;FMOC-L-DAP(MTT)-OH;FMOC-N-BETA-4-METHYLTRITYL-L-2,3-DIAMINOPROPIONIC ACID
CAS NO:654670-89-0
Molecular Formula: C38H34N2O4
Molecular Weight: 582.69
EINECS: N/A
Product Categories: amino acid;Unusual Amino Acids;amino acids
Mol File: 654670-89-0.mol

Chemical Properties

Melting Point: N/A
Boiling Point: 774.3±60.0 °C(Predicted)
Flash Point: N/A
Appearance: /
Density: 1.234±0.06 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: Store at 0°C
Solubility: Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
PKA: 2.69±0.18(Predicted)
CAS DataBase Reference: FMOC-DAP(MTT)-OH(CAS DataBase Reference)
NIST Chemistry Reference: FMOC-DAP(MTT)-OH(654670-89-0)
EPA Substance Registry System: FMOC-DAP(MTT)-OH(654670-89-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: IRRITANT
PackingGroup: N/A
Hazardous Substances Data: 654670-89-0(Hazardous Substances Data)

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Usage
SDS
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654670-89-0 Usage

Uses

Used in Pharmaceutical Industry:
FMOC-DAP(MTT)-OH is used as a building block for the synthesis of cyclic peptides that target the substrate recruitment site of cyclin-dependent kinase (CDK) complexes. These cyclic peptides have the potential to act as inhibitors, disrupting the activity of CDKs, which are often overexpressed in various types of cancer cells. By inhibiting CDKs, these cyclic peptides can help regulate cell cycle progression and prevent uncontrolled cell division, a hallmark of cancer.
Additionally, FMOC-DAP(MTT)-OH can be employed in the development of other bioactive peptides and peptidomimetics with diverse applications in the pharmaceutical industry, such as targeting specific protein-protein interactions, modulating enzyme activity, or serving as potential drug candidates for various therapeutic areas.

Check Digit Verification of cas no

The CAS Registry Mumber 654670-89-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,5,4,6,7 and 0 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 654670-89:
(8*6)+(7*5)+(6*4)+(5*6)+(4*7)+(3*0)+(2*8)+(1*9)=190
190 % 10 = 0
So 654670-89-0 is a valid CAS Registry Number.

654670-89-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name	Fmoc-(N-β-4-methyltrityl)-L-α,β-diaminopropionic acid

1.2 Other means of identification

Product number	-
Other names	Fmoc-Dap(Mtt)-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:654670-89-0 SDS

654670-89-0Upstream product

654670-89-0Downstream Products

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