654673-24-2Relevant academic research and scientific papers
Iron-Catalyzed α-Alkylation of Ketones with Alcohols
Elangovan, Saravanakumar,Sortais, Jean-Baptiste,Beller, Matthias,Darcel, Christophe
supporting information, p. 14483 - 14486 (2016/01/25)
A general and benign iron-catalyzed α-alkylation reaction of ketones with primary alcohols has been developed. The key to success of the reaction is the use of a Kn?lker-type complex as catalyst (2 mol %) in the presence of Cs2CO3 as base (10 mol %) under hydrogen-borrowing conditions. Using 2-aminobenzyl alcohol as alkylation reagent allows for the "green" synthesis of quinoline derivatives.
Selective 1,4-reduction of chalcones with Zn/NH4Cl/C 2H5OH/H2O
Li, Jian-Ping,Zhang, Yong-Xia,Ji, Yan
, p. 390 - 393 (2008/12/20)
In this paper, the Zn/NH4Cl/C2H5OH/H 2O system was applied for the selective 1,4-reduction of chalcones undermild conditions with high selectivity. Themerit lies in inexpensive reagent, simple operation and envi
CHEMICAL COMPOUNDS
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Page 88, (2010/02/06)
Compounds of formula (I):wherein variable groups are as defined within; for use in the inhibition of 11betaHSD1 are described
