654673-32-2Relevant academic research and scientific papers
Enantioselective Synthesis of Substituted δ-Lactones by Cooperative Oxidative N-Heterocyclic Carbene and Lewis Acid Catalysis
Bera, Srikrishna,Daniliuc, Constantin G.,Studer, Armido
, p. 4940 - 4943 (2015)
Efficient construction of complex cylcopentane- or cyclohexane-fused δ-lactones employing redox activation of enals using a chiral N-heterocyclic carbene and LiCl as cooperative catalysts is described. The organocascade proceeds with excellent diastereo- (>99:1) and enantioselectivity (up to >99% ee) and comprises the formation of three bonds with three contiguous stereocenters.
Rhodium-catalyzed cyclization reactions of γ-alkynyl aldehydes with carboxylic acid anhydrides
Tajima, Yuki,Kobayashi, Masayuki,Noguchi, Keiichi,Tanaka, Ken
supporting information, p. 5266 - 5271 (2013/09/02)
It has been established that a cationic rhodium(I)/H8-binap or binap complex catalyzes two different modes of cyclization of γ-alkynyl aldehydes with carboxylic acid anhydrides to give cyclic aldehyde gem-dicarboxylates and cyclic alkenyl ester
Catalytic Asymmetric Intramolecular α-Alkylation of Aldehydes
Vignola, Nicola,List, Benjamin
, p. 450 - 451 (2007/10/03)
The development of a general catalytic asymmetric aldehyde α-alkylation reaction constitutes a major challenge in organic synthesis. Here, we report the first and successful approach toward its solution: (S)-α-methyl proline catalyzes the intramolecular a
