654680-62-3

Usage

Uses

Used in Organic Synthesis:
(1R,3R,4S,6S)-4-TERT-BUTOXYCARBONYLAMINO-4,7,7-TRIMETHYL-BICYCLO[4.1.0]HEPTANE-3-CARBOXYLIC ACID is used as a building block in organic synthesis for the creation of various organic compounds.
Used in Pharmaceutical Preparation:
(1R,3R,4S,6S)-4-TERT-BUTOXYCARBONYLAMINO-4,7,7-TRIMETHYL-BICYCLO[4.1.0]HEPTANE-3-CARBOXYLIC ACID is used as a starting material for the preparation of pharmaceuticals, potentially contributing to the development of new drugs and therapeutic agents.

InChI:InChI=1/C16H27NO4/c1-14(2,3)21-13(20)17-16(6)8-11-9(15(11,4)5)7-10(16)12(18)19/h9-11H,7-8H2,1-6H3,(H,17,20)(H,18,19)/t9-,10+,11+,16+/m1/s1

Upstream product

• 655236-18-3 (1R,3R,5S,7S)-4,4,7-trimethyl-8-azatricyclo[5.2.0.0^3,5]nonan-9-one 
• 498-15-7 (+)-Δ³-carene 
• 654680-57-6 tert-butyl (1R,3R,5S,7S)-4,4,7-trimethyl-9-oxo-8-azatricyclo[5.2.0.0^3,5]nonane-8-carboxylate 

Downstream Products

• 654681-00-2 (1R,3R,4S,6S)-4,7,7-Trimethyl-4-(3-phenyl-ureido)-bicyclo[4.1.0]heptane-3-carboxylic acid methyl ester 
• 654680-90-7 (1R,3R,4S,6S)-4,7,7-Trimethyl-4-(3-phenyl-thioureido)-bicyclo[4.1.0]heptane-3-carboxylic acid methyl ester 
• 654681-11-5 (1S,3S,4R,6R)-1-(4-hydroxymethyl-3,7,7-trimethylbicyclo[4.1.0]hept-3-yl)-3-phenylthiourea 
• 654680-86-1 (1R,3R,4S,6S)-4-amino-4,7,7-trimethylbicyclo[4.1.0]heptane-3-carboxylic acid 
• 654680-82-7 {(1R,3R,4S,6S)-4-amino-4,7,7-trimethylbicyclo[4.1.0]heptan-3-yl}methanol 

Relevant academic research and scientific papers

Synthesis and transformation of novel cyclic β-amino acid derivatives from (+)-3-carene

The regio- and stereoselective addition of chlorosulfonyl isocyanate to (+)-3-carene 1 resulted in β-lactam 2, which was converted to N-Boc-β-amino acid 4, β-amino ester 7, and carboxamide derivatives 18 and 20 via N-Boc activation and mild ring opening.