65473-82-7Relevant academic research and scientific papers
MARKED EFFECT OF A CATALYTIC AMOUNT OF AN AMINE ON SELECTIVE EPOXIDATION OF ALIPHATIC AND AROMATIC OLEFINS WITH t-BUTYL HYDROPEROXIDE AND A MOLYBDENUM OXIDE CHELATE
Kato, Jun-ichi,Ota, Hisanori,Matsukawa, Kazuhiro,Endo, Tadashi
, p. 2843 - 2846 (1988)
In the presence of a catalytic amount of an appropriate amine, epoxides were selectively obtained in good yields from reaction of aliphatic and aromatic olefins with t-butyl hydroperoxide and MoO2(acac)2 in carbon tetrachloride.
A General Regioselective Synthesis of Alcohols by Cobalt-Catalyzed Hydrogenation of Epoxides
Beller, Matthias,Junge, Kathrin,Leischner, Thomas,Li, Wu,Liu, Weiping
supporting information, p. 11321 - 11324 (2020/05/16)
A straightforward methodology for the synthesis of anti-Markovnikov-type alcohols is presented. By using a specific cobalt triphos complex in the presence of Zn(OTf)2 as an additive, the hydrogenation of epoxides proceeds with high yields and selectivities. The described protocol shows a broad substrate scope, including multi-substituted internal and terminal epoxides, as well as a good functional-group tolerance. Various natural-product derivatives, including steroids, terpenoids, and sesquiterpenoids, gave access to the corresponding alcohols in moderate-to-excellent yields.
