65479-24-5Relevant academic research and scientific papers
COMBINATION OF HEPATITIS B VIRUS (HBV) VACCINES AND PYRIDOPYRIMIDINE DERIVATIVES
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Page/Page column 368; 369, (2021/01/22)
Therapeutic combinations of hepatitis B virus (HBV) vaccines and a pyridopyrimidine derivative are described. Methods of inducing an immune response against HBV or treating an HBV-induced disease, particularly in individuals having chronic HBV infection, using the disclosed therapeutic combinations are also described. The invention provides therapeutic combinations or compositions and methods for inducing an immune response against hepatitis B viruses (HBV) infection.
TOLL LIKE RECEPTOR MODULATOR COMPOUNDS
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Paragraph 0963-0966, (2016/10/27)
The present disclosure relates generally to toll like receptor modulator compounds, such as diamino pyrido[3,2 D]pyrimidine compounds and pharmaceutical compositions which, among other things, modulate toll-like receptors (e.g. TLR-8), and methods of making and using them.
Etude de la stereochimie de la reaction de cycloaddition dipolaire-1,3 de quelques 5-phenyl-3,6-dihydro-2H-1,4-oxazin-2-ones avec les N-methyl et N-phenylmaleimides
Monnier, Karin,Schmitt, Gerard,Laude, Bernard,Mercier, Marie-France,Kubicki, Marek M.,Jannin, Michel
, p. 181 - 190 (2007/10/02)
Six derivatives of 5-phenyl-3,4-dihydro-2H-1,4-oxazin-2-ones 1 were synthetized from α-amino acids.These compounds are precursors of six-membered cyclic azomethine ylids involving one stereocenter.The 1,3-dipolar species react with N-methyl and N-phenylma
