65493-55-2

Basic information

• Product Name: Piperazinone, 4-(1-oxopropyl)- (9CI)
• Synonyms: Piperazinone, 4-(1-oxopropyl)- (9CI);4-PROPANOYLPIPERAZIN-2-ONE
• CAS NO: 65493-55-2
• Molecular Formula: C₇H₁₂N₂O₂
• Molecular Weight: 156.18238
• Product Categories: PIPERIDINE
• Mol File: 65493-55-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Piperazinone, 4-(1-oxopropyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazinone, 4-(1-oxopropyl)- (9CI)(65493-55-2)
• EPA Substance Registry System: Piperazinone, 4-(1-oxopropyl)- (9CI)(65493-55-2)

Safety Data

• Hazardous Substances Data: 65493-55-2(Hazardous Substances Data)

Upstream product

• 5625-67-2 2-Ketopiperazine 
• 123-62-6 propionic acid anhydride 

Downstream Products

• 1016538-54-7 C₁₄H₁₆N₂O₃ 

Relevant articles and documents

Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers

A series of 2-oxopiperazine, 4-aminomethyl-, 3-amino- and 3-aminomethylpiperidine analogues of DM235 (sunifiram) and MN19 (sapunifiram), two previously reported potent cognition-enhancers, have been synthesized and tested in the mouse passive-avoidance test. The compounds display minimal effective doses in the range 0.3-10 mg/kg. Although the new substances do not show improved activity when compared to the parent compounds, some useful information has been obtained to understand structure-activity relationships. In addition, the 3-aminopiperidine moiety appears to be a promising scaffold to synthesize new drugs endowed with cognition-enhancing activity.