655-30-1

Basic information

• Product Name: 2,2-dichloro-1-(4-chlorophenyl)-2-fluoroethanone
• CAS NO: 655-30-1
• Molecular Formula: C₈H₄Cl₃FO
• Molecular Weight: 241.4742
• Mol File: 655-30-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 279.1°C at 760 mmHg
• Flash Point: 122.6°C
• Density: 1.498g/cm³
• Vapor Pressure: 0.00409mmHg at 25°C
• Refractive Index: 1.545
• CAS DataBase Reference: 2,2-dichloro-1-(4-chlorophenyl)-2-fluoroethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dichloro-1-(4-chlorophenyl)-2-fluoroethanone(655-30-1)
• EPA Substance Registry System: 2,2-dichloro-1-(4-chlorophenyl)-2-fluoroethanone(655-30-1)

Safety Data

• Hazardous Substances Data: 655-30-1(Hazardous Substances Data)

Usage

Organochlorine compound

Yes, it is a man-made chemical containing chlorine

Physical state

Colorless liquid

Odor

Pungent

Flammability

Flammable

Health hazards

Potential irritant to skin, eyes, and respiratory system; harmful if ingested or inhaled

Environmental hazards

Potentially hazardous to the environment

Uses

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Handling precautions

Handle with care and follow proper safety protocols

Upstream product

• 354-19-8 dichlorofluoroacetic acid 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 394-57-0 2,2-dichloro-1-(4-chloro-phenyl)-2-fluoro-ethanol 
• 2837-90-3 sodium 2,2-dichloro-2-fluoroacetate 

Downstream Products

• 1868-91-3 2,2-dichloro-1,1-bis-(4-chloro-phenyl)-2-fluoro-ethanol 
• 16630-03-8 trans-2-Fluor-2-chlor-1-(4-chlor-phenyl)-ethylen 
• 16630-02-7 cis-2-Fluor-2-chlor-1-(4-chlor-phenyl)-ethylen 
• 16629-95-1 1,2,2-Trichlor-2-fluor-1-<4-chlor-phenyl>-ethan 
• 394-57-0 2,2-dichloro-1-(4-chloro-phenyl)-2-fluoro-ethanol 

Relevant articles and documents

A high performance oxidation method for secondary alcohols by inductive activation of TEMPO in combination with pyridine-bromine complexes

A new TEMPO-mediated catalytic oxidation method in combination with Py·HBr3 (stoichiometric) is developed for oxidation of secondary alcohols to the corresponding ketones. The performance of this oxidizing system is better compared with that of TEMPO method combined with R4NBr3. Poly(4-vinylpyridine)·HBr3 can be used in place of Py·HBr3. The electron-withdrawing substituent at the C-4 position of TEMPO increases the reactivity of TEMPO significantly in the oxidation of electron-deficient alcohols such as polyhaloalkylmethanols. Inductive effect of the substituent of TEMPO is discussed through the characterization of the redox potential of N-O radical by cyclic voltammetry.