65515-24-4

Usage

Chemical compound

3-Methoxy-6-Methyl-2-pyridinecarboxylic acid Methyl ester

Family

Pyridinecarboxylic acid ester

Derivative of

3-Methoxy-6-Methyl-2-pyridinecarboxylic acid

Use

Intermediate in synthesis of pharmaceutical compounds

Studied for

Biological activities and pharmacological properties

Potential effects

Anti-inflammatory and antioxidant

Physical state

Colorless to pale yellow liquid

Odor

Characteristic

Solubility

Soluble in organic solvents

Chemical structure

Pyridine ring with methyl and methoxy groups, carboxylic acid group, and methyl ester group

Applications

Pharmaceutical and chemical industries

Upstream product

• 61548-52-5 3-hydroxy-6-methyl-pyridine-2-carboxylic acid methyl ester 
• 74-88-4 methyl iodide 

Relevant academic research and scientific papers

2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME

The present invention relates with 2-substituted heterocyclic compounds and antitumor composition comprising the same. The compound according to the present invention exhibits superior effect as telomerase inhibitor based on new mechanism (terlomere-terlomerase) which can resolve the problems occurring at the time of using chemotherapeutics, i.e side effects and cross resistance between related mechanism on using chemotherapeutics. In addition, the antitumor composition comprising the compound of the present invention exhibits superior effect in inhibiting the growth of cancer cell.

Antiemetic, psychosomatic and antipsychotic heterocyclic pyridine carboxamides

The present invention provides new basically substituted pyridinecarboxamides having the formula I STR1 wherein R1 represents lower alkyl and --OR1 is in the adjacent position to the carboxamide group, R2 represents lower alkyl or an ethylene radical which is attached to one of the trivalent radicals designated as A and the nitrogen atom located between it to form a 6-membered ring, A represents a divalent saturated hydrocarbon radical which encompasses at most a single ring with 5 or 6 ring members and contains not more than 7 carbon atoms and whose two linkage positions are separated by (3-m) to 4 carbon atoms, or, if R2 is an ethylene radical, represents the 1-propanyl-3-ylidene radical, if m s 1, or the 1,2,4-butane-triyl radical, if m is 0, And one of the factors m and n is 0 and the other is 1, and, if desired, the ring B is further substituted, and the acid addition salts of the compounds of the formula I. These new substances possess useful pharmacological properties, in particular antiemetic, psychosomatic and antipsychotic activity and can be used for the treatment of thought disturbances and of states of psychomotor excitation. Specific embodiments are N-[(1-ethyl-2-pyrrolidinyl)-methyl]-2,6-dimethoxynicotinamide and the pharmaceutically acceptable acid addition salts thereof.