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DL-Canaline dihydrochloride is a synthetic analog of L-canavanine, a non-protein amino acid found in certain legumes. It is a potent and irreversible inhibitor of ornithine decarboxylase, an enzyme involved in the biosynthesis of polyamines. Polyamines are essential for cell growth, proliferation, and differentiation, and their dysregulation is associated with various diseases, including cancer. DL-Canaline dihydrochloride has demonstrated the ability to inhibit cell growth and induce apoptosis in cancer cell lines, positioning it as a promising candidate for the development of new anticancer therapies. Furthermore, it has been explored for its potential to modulate immune responses and as a research tool for studying polyamine metabolism.

65518-20-9

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65518-20-9 Usage

Uses

Used in Pharmaceutical Industry:
DL-Canaline dihydrochloride is used as a research compound for studying the role of ornithine decarboxylase and polyamines in cell growth and proliferation. Its ability to inhibit ornithine decarboxylase makes it a valuable tool for understanding the mechanisms of polyamine biosynthesis and its implications in various diseases.
Used in Cancer Research and Therapy:
DL-Canaline dihydrochloride is used as an anticancer agent for its potential to inhibit cell growth and induce apoptosis in cancer cell lines. Its irreversible inhibition of ornithine decarboxylase disrupts polyamine biosynthesis, which is crucial for cancer cell survival and proliferation. This property makes DL-Canaline dihydrochloride a promising candidate for the development of new anticancer therapies targeting polyamine metabolism.
Used in Immunology Research:
DL-Canaline dihydrochloride is used as an immunomodulatory agent in the study of immune responses. Its potential to modulate immune responses has been investigated, providing insights into the role of polyamines in immune system regulation and the development of immunotherapies.
Used in Metabolic Research:
DL-Canaline dihydrochloride is used as a tool in the study of polyamine metabolism, helping researchers to understand the biosynthetic pathways and regulatory mechanisms of polyamines. This knowledge can contribute to the development of targeted therapies for diseases associated with polyamine dysregulation.

Check Digit Verification of cas no

The CAS Registry Mumber 65518-20-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,5,1 and 8 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 65518-20:
(7*6)+(6*5)+(5*5)+(4*1)+(3*8)+(2*2)+(1*0)=129
129 % 10 = 9
So 65518-20-9 is a valid CAS Registry Number.

65518-20-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-4-aminooxybutanoic acid,dihydrochloride

1.2 Other means of identification

Product number -
Other names 2-Amino-4-(aminooxy)butanoic acid dihydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:65518-20-9 SDS

65518-20-9Upstream product

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