655228-07-2

Upstream product

• 27825-20-3 methyl 3-oxo-3,4-dihydropyrazine-2-carboxylate 
• 108-20-3 di-isopropyl ether 
• 156715-24-1 1,5-anhydro-4,6-O-benzylidene-3-deoxy-2-(p-tolylsulfonyl)-D-ribo-hexitol 

Relevant academic research and scientific papers

Novel pyrazine derivatives or salts thereof, pharmaceutical composition containing the same, and production intermediates thereof

Pyrazine derivatives represented by general formula [1]: 1wherein the variables are as defined in the specification, or salts thereof have an excellent antiviral activity and are useful as a therapeutic agent for treating viral infections. Further, fluoropyrazine-carboxamide derivatives represented by general formula [2]: 2wherein the variables are as defined in the specification, or salts thereof are useful as an intermediate for production of the compounds of general formula [1], and as an intermediate for production of the fluoropyrazine-carboxamide derivatives of which one typical example is 6-fluoro-3-hyroxy-2-pyrazine-carboxamide having an antiviral activity.