655229-65-5Relevant academic research and scientific papers
A clay-mediated, regioselective synthesis of 2-(aryl/alkyl)amino- thiazolo[4,5-c]carbazoles
Chakrabarty, Manas,Ghosh, Nandita,Harigaya, Yoshihiro
, p. 4955 - 4957 (2004)
The 3-aminocarbazoles 1a-e were condensed with phenyl and benzyl isothiocyanates on montmorillonite K10 clay or TLC-grade silica gel at room temperature to furnish efficiently the N-phenyl and N- benzylthioureidocarbazoles, 2a-e and 2f, respectively, within minutes. When adsorbed on montmorillonite K10 clay impregnated with para-toluene sulfonic acid (1:1, w/w) and heated at 60-70°C, 2a-e and 2f furnished the 2-anilino and 2-benzylaminothiazolo[4,5-c]carbazoles, 3a-e and 3f, respectively, regioselectively in high yields. The cyclisation was also effective for the N-methylthioureidocarbazoles 2g-i.
A novel, expedient synthesis of thiazolo[4,5-c]- and -[5,4-b]carbazoles
Chakrabarty, Manas,Ghosh, Nandita,Harigaya, Yoshihiro
, p. 779 - 786 (2007/10/03)
A new synthesis of thiazolo[4,5-c]- and -[5,4-b]carbazoles (6a-e, 7a, 8b-e) was accomplished from 3-aminocarbazoles (3a-e) by separate condensations with methyl and phenyl isothiocyanates, followed by oxidative cyclization of the resulting thioureidocarba
