65528-98-5 Usage
Bioactive lipid molecule
LPA is a naturally occurring compound that has biological activity and can interact with cells in the body.
Derivative of phospholipids
LPA is chemically derived from phospholipids, which are a major component of cell membranes.
Potent signaling molecule
LPA acts as a signaling molecule that can regulate various cellular processes, such as cell growth, survival, and migration.
Involvement in physiological and pathological processes
LPA plays a role in various physiological processes, such as vascular development and immune response, as well as pathological processes, such as cancer progression.
Interaction with G protein-coupled receptors
LPA exerts its effects by interacting with specific G protein-coupled receptors on the surface of cells.
Potential therapeutic target
LPA has been suggested as a potential target for therapeutic intervention in diseases such as cancer and fibrosis.
Role in neurodegenerative diseases
1-Oleoyl LPA has been investigated for its potential role in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease.
Biomarker for pathological conditions
1-Oleoyl LPA has been studied as a potential biomarker for various pathological conditions, including cancer and cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 65528-98-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,5,2 and 8 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 65528-98:
(7*6)+(6*5)+(5*5)+(4*2)+(3*8)+(2*9)+(1*8)=155
155 % 10 = 5
So 65528-98-5 is a valid CAS Registry Number.
65528-98-5Relevant articles and documents
Biosynthesis of castor oil: Effect of polyamines on the acylation of lysophosphatidic acid at the sn-2 position with ricinoleic acid
Tomosugi, Mitsuhiro,Ohshiro, Akane,Hara, Shin'ichiro,Ichihara, Ken'ichi
, p. 2052 - 2056 (2008/02/13)
Polyamines with diamine structures of chain length longer than 3C were essential for the synthesis of phosphatidic acid (PA) from ricinoleoyl-CoA and lysophosphatidic acid (LPA) by the castor LPA acyltransferase reaction, suggesting that polyamines modulate enzyme affinity for the acyl-CoA substrate in vivo.
Osteoblast-specific mitogens and drugs containing such compounds
-
, (2008/06/13)
Osteoblast-specific mitogens and drugs containing such compounds can be used for treating metabolic bone diseases. These compounds include lysophosphatidylic acid derivatives selected from the group consisting of compounds of formula: wherein R1=alkenyl or alkynyl having from 6 to 24 carbon atoms; n=0-12; X=oxygen or NH; the compounds (all-cis-5,8,11,14)-eicosatetraenoic acid 2-hydroxy-3-phosphonooxypropyl ester; cis-9, cis-12-octadecadienoic acid 2-hydroxy-3-phosphonooxypropyl ester; (all-cis-9,12,15)-octadecatrienoic acid 2-hydroxy-3-phosphonooxypropyl ester; cis-9-octadecenoic acid 2-hydroxy-3-phosphonooxypropyl ester; and erucic acid 2-hydroxy-3-phosphonooxypropylester being excluded, and the physiologically tolerable salts, esters, optically active forms, and racemates of said compounds, and derivatives of said compounds, salts, esters, optically active forms and racemates which can be metabolized in vivo to yield the corresponding compound of formula (I).
