65541-93-7Relevant academic research and scientific papers
Development of a sensitive and selective fluorescent probe for Zn2+ based on naphthyridine Schiff base
Li, Chao-rui,Wang, Guan-qun,Fan, Long,Li, Si-liang,Qin, Jing-can,Yang, Zheng-yin
, p. 231 - 236 (2019)
In this study, bearing 4-methyl-7-acetamide-1,8-naphthyridyl group as the fluorophore and the receptor, we designed and synthesized a new-type Schiff-base ligand 1 which was identified as a Zn2+ fluorescent probe. The excellent selectivity and high sensitivity of this as-synthesized fluorescent probe 1 towards Zn2+ over other various biogenic metal ions were observed, for that only Zn2+ induced a drastic enhancement by about 63-fold in intensity of fluorescence emission at 504 nm, and the limit of detection (LOD) could reach 7.52 nM. Moreover, the formation of a 2:1 complex between this probe 1 and Zn2+ was determined, and the perfect invertibility and renewability of this probe 1 for sensing Zn2+ were also demonstrated. As a result, the practical applications of 1 were broadened for sensing and monitoring Zn2+ environmentally and biologically.
A novel Schiff-base fluorescent probe based on 1,8-naphthyridine and naphthalimide for Al3+
Yue, Xiao-li,Li, Chao-rui,Yang, Zheng-yin
, p. 167 - 171 (2017/05/29)
A novel Schiff-base, 7-acetamino-4-methyl-1,8-naphthyridine-2-carbaldehyde-(1′,8′-naphthalenedicarbonyl) hydrazone (HL) was designed, synthesized and evaluated as a fluorescent probe. The fluorescence properties of this probe towards various metal ions were investigated by UV–vis and fluorescence spectra in methanol. Test results indicated that the probe had high selectivity towards Al3+ over other commonly coexisting metal ions. Upon addition of Al3+, the fluorescence intensity at 414?nm increased significantly due to the inhibition of the PET process. The binding constant (Ka) of Al3+ binding to HL was calculated to be 5.64?×?104?M?1 from a Benesi-Hildebrand plot, and the detection limit (LOD) of HL for sensing Al3+ was calculated to be 0.13?μM. The binding stoichiometry between HL and Al3+ was determined as 1:1 by the Job's plot. Furthermore, the probe was chemically reversible for Al3+ in methanol by the addition of Na2EDTA solution.
Methylene bridging 1,8-naphthyridine ligand and copper (I) complex, preparing method and application
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Paragraph 0043; 0044, (2017/04/26)
The invention discloses a methylene bridging 1,8-naphthyridine ligand and copper (I) complex, a preparing method and an application. The molecular formula of the methylene bridging 1,8-naphthyridine ligand and copper (I) complex is shown in the specificat
1,8-Naphthyridine-Derived Ni2+/Cu2+-Selective fluorescent chemosensor with different charge transfer processses
Li, Zhanxian,Zhao, Wanying,Li, Xiaoya,Zhu, Yanyan,Liu, Chunmei,Wang, Lina,Yu, Mingming,Wei, Liuhe,Tang, Mingsheng,Zhang, Hongyan
, p. 12444 - 12449 (2013/01/15)
A highly fluorescent chemosensor based on 1,8-naphthyridine with high sensitivity and selectivity toward Ni2+/Cu2+ over other cations both in aqueous solution over a wide pH range (4-10) and in cellular environments was developed. Counteranions such as acetate, sulfate, nitrate, and perchlorate have no influence on the detection of such metal ions. Ethylenediamine showed high selectivity toward the in situ-prepared Cu 2+ complex over the Ni2+ complex, which can be applied to distinguish Ni2+ and Cu2+. The Ni2+-induced fluorescence on-off mechanism was revealed to be mediated by intramolecular charge transfer from the metal to the ligand, while that by Cu2+ involves intramolecular charge transfer from the ligand to the metal, as confirmed by picosecond time-resolved fluorescence spectroscopy and time-dependent density functional theory calculations.
Synthesis, structures and spectroscopic properties of new 1,2-bis[2-(4-methyl-7-acetylamino-1,8-naphthyridine)]ethylene ligand and its binuclear copper(I) complexes
Li, Zhan-Xian,Li, Cong,Mu, Wei-Hua,Xiong, Shao-Xiang,Fu, Wen-Fu
experimental part, p. 7 - 15 (2012/02/02)
The synthesis, characterization, spectroscopic properties of a new ligand 1,2-bis[2-(4-methyl-7-acetylamino-1,8-naphthyridine)]ethylene (L) and its two binuclear Cu(I) complexes containing triphenylphosphine (PPh3) or bis(diphenylphosphino)methane (dppm), [Cu2(L)(PPh3) 4](BF4)2·2CH2Cl2 (1·2CH2Cl2) and [Cu2(L)(dppm) 2](BF4)2·4H2O (2·4H2O) are reported. The structural investigation of these compounds based on X-ray crystal analysis shows that the copper(I) centers adopt different coordination geometries, O(N)CuP2+ and NCuP2+ for complexes 1 and 2, respectively. Upon irradiation of a degassed organic solution of L at 365 nm, photoinduced isomerization reaction and an intramolecular proton transfer of ligand L were detailed studied by absorption spectral changes. A spectroscopic investigation involving time-dependent density functional theory calculations allows assignment of the excited states that relate to emission and transient absorption spectra. The observed lower-energy absorption bands appearing in the region of 413 and 418 nm for 1 and 2 in dichloromethane are assigned to ligand-to-ligand charge transfer (LLCT, phosphine → napy) transition in nature. Compared with well-structured solid-state emission originating from ππ transition of ligand L, complexes 1 and 2 exhibit intense room-temperature solid-state emissions with λmax at 586 and 620 nm, respectively. The energy and the shape of the emission bands are clearly different from that of the ligand, indicating the emissions come from different excited states.
