65551-76-0 Usage
Uses
Used in Pharmaceutical Industry:
1-(6-amino-9H-purin-9-yl)-3-[butyl(2-hydroxyethyl)amino]propan-2-ol is used as a therapeutic candidate for the treatment of neurodegenerative diseases such as Parkinson's and Alzheimer's disease. Its adenosine A2A receptor antagonist property makes it a promising agent for managing these conditions.
Used in Oncology:
1-(6-amino-9H-purin-9-yl)-3-[butyl(2-hydroxyethyl)amino]propan-2-ol is also being investigated for its potential use in cancer treatment. It has demonstrated the ability to inhibit tumor growth, making it a candidate for further research and development in oncology.
Check Digit Verification of cas no
The CAS Registry Mumber 65551-76-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,5,5 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 65551-76:
(7*6)+(6*5)+(5*5)+(4*5)+(3*1)+(2*7)+(1*6)=140
140 % 10 = 0
So 65551-76-0 is a valid CAS Registry Number.
65551-76-0Relevant academic research and scientific papers
Salts of 5-methylpyrazole-3-carboxylic acid with basically substituted adenine derivatives/Identification and lipolysis inhibitory activity
Credner,Tauscher,Jozic,Brenner
, p. 2096 - 2100 (2007/10/02)
5-Methylpyrazole-3-carboxylic acid forms salts with basically substituted adenine bases of type (4) or (5), which have significantly more lipolysis inhibitory activity than the free acid itself. The substance tested, 6-amino-9-[2-hydroxy-3-(N-methyl-N-2-hydroxyethyl)-aminopropyl]-purine-5-methylpyrazole-3-carboxylate (16), causes a significant reduction of serum FFA levels in fasted rats, even at the very low dosage of 0.150 mg/kg b.w., whereas the free 5-methyl-pyrazole-3-carboxylic-acid shows significant activity in this model only at doses of 2 mg/kg b.w. and above. The salt also shows similar activity on serum triglycerides. The effects on FFA, triglyceride and cholesterol levels, respectively, in fasted rats lasts for at least 8 h.
