65551-76-0 Usage
General Description
The chemical 1-(6-amino-9H-purin-9-yl)-3-[butyl(2-hydroxyethyl)amino]propan-2-ol, also known as WOBE437, is a compound with a complex structure that includes a purine ring and butyl(2-hydroxyethyl)amino. It has a molecular formula of C18H27N7O2 and a molecular weight of 389.46 g/mol. 1-(6-amino-9H-purin-9-yl)-3-[butyl(2-hydroxyethyl)amino]propan-2-ol is a potent and selective adenosine A2A receptor antagonist, making it a potential therapeutic candidate for the treatment of neurodegenerative diseases, such as Parkinson's and Alzheimer's disease. It is also being investigated for its potential use in cancer treatment due to its ability to inhibit tumor growth. Overall, 1-(6-amino-9H-purin-9-yl)-3-[butyl(2-hydroxyethyl)amino]propan-2-ol has demonstrated promising pharmacological properties and potential medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 65551-76-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,5,5 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 65551-76:
(7*6)+(6*5)+(5*5)+(4*5)+(3*1)+(2*7)+(1*6)=140
140 % 10 = 0
So 65551-76-0 is a valid CAS Registry Number.
65551-76-0Relevant articles and documents
Salts of 5-methylpyrazole-3-carboxylic acid with basically substituted adenine derivatives/Identification and lipolysis inhibitory activity
Credner,Tauscher,Jozic,Brenner
, p. 2096 - 2100 (2007/10/02)
5-Methylpyrazole-3-carboxylic acid forms salts with basically substituted adenine bases of type (4) or (5), which have significantly more lipolysis inhibitory activity than the free acid itself. The substance tested, 6-amino-9-[2-hydroxy-3-(N-methyl-N-2-hydroxyethyl)-aminopropyl]-purine-5-methylpyrazole-3-carboxylate (16), causes a significant reduction of serum FFA levels in fasted rats, even at the very low dosage of 0.150 mg/kg b.w., whereas the free 5-methyl-pyrazole-3-carboxylic-acid shows significant activity in this model only at doses of 2 mg/kg b.w. and above. The salt also shows similar activity on serum triglycerides. The effects on FFA, triglyceride and cholesterol levels, respectively, in fasted rats lasts for at least 8 h.
