65562-43-8

Basic information

• Product Name: (5Z)-3-hexopyranosyl-5-(phenylmethylidene)-2-thioxo-1,3-thiazolidin-4-one
• CAS NO: 65562-43-8
• Molecular Formula: C₁₆H₁₇NO₆S₂
• Molecular Weight: 383.4393
• Mol File: 65562-43-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 628°C at 760 mmHg
• Flash Point: 333.6°C
• Density: 1.66g/cm³
• Vapor Pressure: 1.23E-16mmHg at 25°C
• Refractive Index: 1.765
• CAS DataBase Reference: (5Z)-3-hexopyranosyl-5-(phenylmethylidene)-2-thioxo-1,3-thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5Z)-3-hexopyranosyl-5-(phenylmethylidene)-2-thioxo-1,3-thiazolidin-4-one(65562-43-8)
• EPA Substance Registry System: (5Z)-3-hexopyranosyl-5-(phenylmethylidene)-2-thioxo-1,3-thiazolidin-4-one(65562-43-8)

Safety Data

• Hazardous Substances Data: 65562-43-8(Hazardous Substances Data)

Usage

General Description

(5Z)-3-hexopyranosyl-5-(phenylmethylidene)-2-thioxo-1,3-thiazolidin-4-one is a complex chemical compound that contains a thiazolidine ring and a hexopyranosyl group. The compound also contains a phenylmethylidene group, which is a functional group commonly found in organic compounds. The thiazolidin-4-one ring has potential medicinal properties, and compounds containing this ring have been studied for their anti-inflammatory, anti-cancer, and anti-diabetic activities. The hexopyranosyl group, on the other hand, is a carbohydrate derivative and is often found in natural products. The overall structure of this compound suggests potential pharmaceutical and therapeutic applications, making it a topic of interest in medicinal chemistry research.

Upstream product

• 3806-42-6 5-benzylidene-2-thioxothiazolidin-4-one 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 65562-18-7 N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-5-(3,4-dimethoxybenzylidene)rhodanine 

Relevant articles and documents

N glucopyranosyl 5 aralkylidenerhodanines: Synthesis and antibacterial and antiviral activities

A series of N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-5-aralkylidenerhodanines was synthesized, and the acetyl groups were removed to give N-β-D-glucopyranosyl-5-aralkylidenerhodanines without cleavage of the rhodanine ring by means of acid hydrolysis. Alkaline hydrolysis with ammonia in methanol resulted in cleavage to N-glucosylthiourea, providing evidence for N-glycoside formation. A number of the rhodanine derivatives, especially those with nitro or chloro groups in the aromatic ring, showed antibacterial activity. N-β-D-Glucopyranosyl-5-(4-nitrobenzylidene)rhodanine showed antiviral activity by inhibition of viral RNA synthesis. Some effect on blood sugar levels also was observed with several rhodanines.