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1-METHYL-IMIDAZO[1,5-A]PYRIDINE, also known as 1-Methylimidazo[1,5-a]pyridine (1-MeIP), is a chemical compound that belongs to the family of heterocyclic aromatic amines (HAAs). It is classified as a Group 2B carcinogen by the International Agency for Research on Cancer (IARC) due to its potential to induce DNA damage and increase the risk of developing cancer.

6558-62-9

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6558-62-9 Usage

Uses

1-METHYL-IMIDAZO[1,5-A]PYRIDINE is not used for any specific applications in industries, as it is a harmful substance with carcinogenic, mutagenic, and genotoxic effects. However, efforts to minimize exposure to 1-MeIP are crucial for public health.
Used in Public Health:
1-METHYL-IMIDAZO[1,5-A]PYRIDINE is a concern for public health due to its carcinogenic properties.
1-METHYL-IMIDAZO[1,5-A]PYRIDINE is used as a reference for [reason to minimize exposure] because it is linked to an increased risk of developing cancer, particularly in the colon, prostate, and lung.
Efforts to minimize exposure to 1-METHYL-IMIDAZO[1,5-A]PYRIDINE include:
1. Modifying cooking methods to avoid high-temperature cooking processes such as grilling, smoking, or charbroiling, which can lead to the formation of 1-MeIP in certain meats and fish.
2. Raising awareness about the potential health risks associated with exposure to 1-MeIP, particularly in relation to tobacco smoke and overcooked or charred foods.

Check Digit Verification of cas no

The CAS Registry Mumber 6558-62-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,5,5 and 8 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6558-62:
(6*6)+(5*5)+(4*5)+(3*8)+(2*6)+(1*2)=119
119 % 10 = 9
So 6558-62-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2/c1-7-8-4-2-3-5-10(8)6-9-7/h2-6H,1H3

6558-62-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-methylimidazo[1,5-a]pyridine

1.2 Other means of identification

Product number -
Other names 1-methyl-imidazo[1,5-a]pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6558-62-9 SDS

6558-62-9Downstream Products

6558-62-9Relevant academic research and scientific papers

The reaction of imidazo[1,5-a]pyridines with ninhydrin revisited

El-Abadelah, Mustafa M.,Awwadi, Firas F.,Abdullah, Ahmad H.,Voelter, Wolfgang

, p. 559 - 565 (2020)

The synthesis of 2,2′-(Imidazo[1,5-a]pyridine-1,3-diyl)bis(2-hydroxy-1H-indene-1,3(2H)-dione) (11) is achieved by reaction of imidazo[1,5-a]pyridine (7) with two equivalents of ninhydrin (1) at room temperature. The structure of this new 1,3-bis-adduct 11 is evidenced from HRMS and NMR spectral data and confirmed by single-crystal X-ray crystallography. Employment of equimolar amounts of 1 and 7 gave a separable mixture of the respective 1- A nd 3-monomeric adducts (9, 10).

Preparation method of N- phenyl-2-aminopyrimidine compound and its application

-

, (2017/04/28)

The invention relates to a new N- phenyl-2-aminopyrimidine compound and a medicine composition containing the compound; the N- phenyl-2-aminopyrimidine compound is applied to treat related disease or symptoms of epidermal growth factor receptor (EGFR), such as treat or improve abnormal cell proliferative disease like cancer.

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